Phygrine, an alkaloid from Physalis species

• Published in: Phytochemistry (Oxford) Vol. 31; no. 12; pp. 4173 - 4176
• Main Authors: Basey, Keith, McGaw, Brian A., Woolley, Jack G.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.12.1992; Elsevier
• Subjects: Biochemistry & Molecular Biology; Biological and medical sciences; chemical constituents of plants; Chemical constitution; Fundamental and applied biological sciences. Psychology; Life Sciences & Biomedicine; medicinal plants; molecular conformation; P. angulata; P. edulis; P. ixocarpa; P. minima; P. peruviana; P. philadelphica; P. pruinosa; P. pubescens; P. viscosa; phygrine; Physalis alkekengi; Physalis angulata; Physalis minima; Physalis peruviana; Physalis philadelphica; Physalis pubescens; Plant physiology and development; Plant Sciences; pyrrolidine alkaloid; pyrrolidine alkaloids; roots; Science & Technology; Solanaceae; spectral analysis; P. angulata; P. pruinosa; pyrrolidine alkaloid; P. peruviana; P. philadelphica; P. viscosa; P. ixocarpa; phygrine; P. edulis; P. pubescens; P. minima; Solanaceae; Physalis alkekengi; SOLANACEAE; P-EDULIS; P-PUBESCENS; P-MINIMA; PYRROLIDINE ALKALOID; P-VISCOSA; P-PRUINOSA; P-IXOCARPA; P-PERUVIANA; PHYGRINE; PHYSALIS-ALKEKENGI; P-ANGULATA; P-PHILADELPHICA; Alkaloid; Root; Molecular structure; Physalis; Dicotyledones; Angiospermae; Isolation; Above ground plant part; Spermatophyta; Pyrrolidine derivatives; Medicinal plant
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/0031-9422(92)80437-J

A new alkaloid, phygrine, isolated from the roots and aerial parts of Physalis alkekengi has been shown to be bis-hygrine or 1-[1′-methylpyrrolidine-2′-yl]-3-[1″-methyl-2″-(2″-oxopropyl)pyrrolidine-5″-yl]propan-2-one. The alkaloid is also present in P. angulata, P. philadelphica, P. ixocarpa, P. edulis, P. peruviana, P. minima, P. pubescens, P. viscosa and P. pruinosa.