A prospective study of prenatal mercury exposure from maternal dental amalgams and autism severity

Dental amalgams containing 50% mercury (Hg) have been used in dentistry for the last 150 years, and Hg exposure during key developmental periods was associated with autism spectrum disorders (ASDs). This study examined increased Hg exposure from maternal dental amalgams during pregnancy among 100 qu...

Full description

Saved in:
Bibliographic Details
Published inActa neurobiologiae experimentalis Vol. 69; no. 2; pp. 189 - 197
Main Authors Geier, David, Kern, Janet, Geier, Mark
Format Journal Article
LanguageEnglish
Published Poland 01.01.2009
Subjects
Autistic Disorder - chemically induced
Autistic Disorder - classification
Child
Dental Amalgam - toxicity
Female
Humans
Logistic Models
Male
Maternal Exposure
Maternal-Fetal Exchange - physiology
Mental Status Schedule
Pregnancy
Prospective Studies
Severity of Illness Index
Online AccessGet full text

Cover

More Information
Summary:Dental amalgams containing 50% mercury (Hg) have been used in dentistry for the last 150 years, and Hg exposure during key developmental periods was associated with autism spectrum disorders (ASDs). This study examined increased Hg exposure from maternal dental amalgams during pregnancy among 100 qualifying participants born between 1990-1999 and diagnosed with DSM-IV autism (severe) or ASD (mild). Logistic regression analysis (age, gender, race, and region of residency adjusted) by quintile of maternal dental amalgams during pregnancy revealed the ratio of autism:ASD (severe:mild) were about 1 (no effect) for =6 amalgams. Subjects with >=6 amalgams were 3.2-fold significantly more likely to be diagnosed with autism (severe), in comparison to ASD (mild), than subjects with
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0065-1400
1689-0035
DOI:10.55782/ane-2009-1744