Improvement of sleep architecture in PD with subthalamic nucleus stimulation

• Published in: Neurology Vol. 55; no. 11; p. 1732
• Main Authors: Arnulf, I, Bejjani, B P, Garma, L, Bonnet, A M, Houeto, J L, Damier, P, Derenne, J P, Agid, Y
• Format: Journal Article
• Language: English
• Published: United States 12.12.2000
• Subjects: Adult; Electric Stimulation; Female; Humans; Male; Middle Aged; Parkinson Disease - physiopathology; Reaction Time - physiology; Sleep - physiology; Subthalamic Nucleus - physiopathology

High-frequency stimulation of the subthalamic nucleus (STN) was used to investigate the relationship of sleep disorders with motor handicap in PD. In 10 insomniac patients with PD, stimulation reduced nighttime akinesia by 60% and completely suppressed axial and early morning dystonia, but did not a...