Analysis of cyanobacterial toxins by physicochemical and biochemical methods

Cyanobacteria (blue-green algae) produce a wide range of low molecular weight metabolites that include potent neurotoxins, hepatotoxins, and cytotoxins. The accumulation of such toxins in freshwaters, and in brackish and marine waters presents hazards to human and animal health by a range of exposur...

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Bibliographic Details
Published inJournal of AOAC International Vol. 84; no. 5; p. 1626
Main Authors Codd, G A, Metcalf, J S, Ward, C J, Beattie, K A, Bell, S G, Kaya, K, Poon, G K
Format Journal Article
LanguageEnglish
Published England 01.09.2001
Subjects
Bacterial Toxins - analysis
Chemical Phenomena
Chemistry, Physical
Cyanobacteria - chemistry
Immunoassay
Microcystins
Peptides, Cyclic - analysis
Toxins, Biological - analysis
Toxins, Biological - chemistry
Water Supply - analysis
Water Supply - standards
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Summary:Cyanobacteria (blue-green algae) produce a wide range of low molecular weight metabolites that include potent neurotoxins, hepatotoxins, and cytotoxins. The accumulation of such toxins in freshwaters, and in brackish and marine waters presents hazards to human and animal health by a range of exposure routes. A review is presented of developments in the detection and analysis of cyanobacterial toxins, other than bioassays, including application of physicochemical, immunoassays, and enzyme-based methods. Analytical requirements are considered with reference to recently derived guideline levels for the protection of health and to the availability, or otherwise, of purified, quantitative cyanobacterial toxin standards.
ISSN:1060-3271
DOI:10.1093/jaoac/84.5.1626