Flurbiprofen in dysmenorrhea

Reports on the efficacy of flurbiprofen for dysmenorrhea conflict. We gave 59 dysmenorrheic patients flurbiprofen (50 mg), aspirin (650 mg), or placebo. Paired drug comparisons showed that patients preferred flurbiprofen and that it was more effective in relief of pain, in allowing patients to pursu...

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Bibliographic Details
Published inClinical pharmacology and therapeutics Vol. 32; no. 1; p. 76
Main Authors DeLia, J E, Emery, M G, Taylor, R H, Scott, J R
Format Journal Article
LanguageEnglish
Published United States 01.07.1982
Subjects
Adolescent
Adult
Aspirin - therapeutic use
Drug Evaluation
Dysmenorrhea - drug therapy
Female
Flurbiprofen - adverse effects
Flurbiprofen - therapeutic use
Humans
Propionates - therapeutic use
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Summary:Reports on the efficacy of flurbiprofen for dysmenorrhea conflict. We gave 59 dysmenorrheic patients flurbiprofen (50 mg), aspirin (650 mg), or placebo. Paired drug comparisons showed that patients preferred flurbiprofen and that it was more effective in relief of pain, in allowing patients to pursue normal daily function, and in reducing the need for additional analgesics. Except in patient preference, aspirin was only marginally superior to placebo, There was an increase in minor side effects in the flurbiprofen group, but our results indicate therapeutic utility for flurbiprofen in dysmenorrhea.
ISSN:0009-9236
DOI:10.1038/clpt.1982.129