Recent Developments in Microwave-Assisted, Transition-Metal-Catalysed C-C and C-N Bond-Forming Reactions

• Published in: European Journal of Organic Chemistry Vol. 2008; no. 7; pp. 1133 - 1155
• Main Authors: Appukkuttan, Prasad, Van der Eycken, Erik
• Format: Book Review Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.03.2008; WILEY‐VCH Verlag
• Subjects: C-C coupling; Chemistry; Cross-coupling; Kemi; Microwave reactions; NATURAL SCIENCES; NATURVETENSKAP; Palladium; Transition metals
• ISSN: 1434-193X; 1099-0690; 1099-0690
• DOI: 10.1002/ejoc.200701056

A selective overview of the recent developments of microwave‐assisted, transition‐metal‐catalysed C–C and C–N bond‐forming reactions is presented. Microwave‐assisted chemistry is a comparatively novel technique in the present‐day synthetic world and has recently grown in an exponential manner, stretching from academia to a widely practiced technique in industry. Transition‐metal‐catalysed C–C and C–N bond‐forming reactions represent one of the most interesting and well‐investigated type of microwave‐assisted reactions, evident from the plethora of available literature and patents in this area. Given the large number of articles published on the subject, we have made a very concise selection from the recent literature, covering manuscripts dealing with the subject from the period of the end 2004 until the first part of 2007.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) A selective survey on the recent developments of microwave‐assisted transition‐metal‐catalysed C–C and C–N bond‐forming reactions is presented. This reviewencompasses the advances in the last threeyears of Suzuki, Stille, Heck and Sonogashira couplings, carbonylations, Buchwald–Hartwig aminations, click chemistry and some other related areas.