Specific Design of Titanium(IV) Phenolato Chelates Yields Stable and Accessible, Effective and Selective Anticancer Agents

Invited for the cover of this issue is the group of Edit Y. Tshuva at The Hebrew University of Jerusalem and co‐workers. The image depicts a phenolato titanium(IV) complex as the Joker that combines four qualities essential for an anticancer drug: stability, efficacy, accessibility and selectivity....

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Bibliographic Details
Published inChemistry : a European journal Vol. 22; no. 29; p. 9849
Main Authors Meker, Sigalit, Braitbard, Ori, Hall, Matthew D., Hochman, Jacob, Tshuva, Edit Y.
Format Journal Article
LanguageEnglish
Published Weinheim Blackwell Publishing Ltd 11.07.2016
Wiley Subscription Services, Inc
Subjects
Accessibility
Anticancer properties
Antitumor agents
Cancer
Chelates
Chemistry
Effectiveness
Selectivity
Stability
Texts
Titanium
Workers
Online AccessGet full text

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Summary:Invited for the cover of this issue is the group of Edit Y. Tshuva at The Hebrew University of Jerusalem and co‐workers. The image depicts a phenolato titanium(IV) complex as the Joker that combines four qualities essential for an anticancer drug: stability, efficacy, accessibility and selectivity. Read the full text of the article at 10.1002/chem.201601389. “We were always fascinated with Ti chemistry especially for biological applications, as it is a non‐toxic metal.” Read more about the story behind the cover in the Cover Profile and about the research itself on page 9986 ff. (DOI: 10.1002/chem.201601389).
Bibliography:ark:/67375/WNG-KD8JRWRL-M
ArticleID:CHEM201602626
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ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201602626