Successful treatment with topical imiquimod of anal Buschke-Löwenstein tumor in a child

• Published in: Dermatologic therapy Vol. 28; no. 6; pp. 363 - 365
• Main Authors: Anissa, Zaouak, Houda, Hammami-Ghorbel, Wafa, Koubaa, Olfa, Midassi, Rym, Benmously-Mlika, Achraf, Debbiche, Samy, Fenniche
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2015
• Subjects: Administration, Topical; Aminoquinolines - administration & dosage; anal; Antineoplastic Agents - administration & dosage; Anus Neoplasms - drug therapy; Anus Neoplasms - pathology; Biopsy; Buschke-Lowenstein Tumor - drug therapy; Buschke-Lowenstein Tumor - pathology; Buschke-Löwenstein tumor; child; Child, Preschool; Humans; imiquimod; Male; Remission Induction; safety; Skin Neoplasms - drug therapy; Skin Neoplasms - pathology; treatment; Treatment Outcome; Buschke-Löwenstein tumor; treatment; anal; safety; imiquimod; child
• ISSN: 1396-0296; 1529-8019
• DOI: 10.1111/dth.12261

ABSTRACT Buschke–Lowenstein tumor (BLT) is a large exophytic lesion of the anogenital region with a clinically malignant aspect but a benign histology. Because of its low incidence, this pathology is exceptional in childhood. Surgical excision is the main therapeutic approach. Herein, we report a case of BLT successfully treated with imiquimod in a 2‐year old boy. Young children with BLT should be offered a chance of medical treatment before extensive surgical destruction is used.