Attenuation correction with region growing method used in the positron emission mammography imaging system

The Positron Emission Mammography imaging system （PEMi） provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer co...

Full description

Saved in:
Bibliographic Details
Published inChinese physics C Vol. 39; no. 10; pp. 131 - 138
Main Author 顾笑悦 李琳 尹鹏飞 贠明凯 柴培 黄先超 孙校丽 魏龙
Format Journal Article
LanguageEnglish
Published 01.10.2015
Subjects
Attenuation
Breast
Imaging
Positron emission
Segmentation
Three dimensional
Thresholds
Tumors
X线摄影
分割图像
区域生长法
成像系统
放射性示踪
校正方法
正电子发射
衰减
Online AccessGet full text

Cover

More Information
Summary:The Positron Emission Mammography imaging system （PEMi） provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer concentration map of the breast, a new attenuation correction method based on a three-dimensional seeded region growing image segmentation （3DSRG-AC） method has been developed. The method gives a 3D connected region as the segmentation result instead of image slices. The continuity property of the segmentation result makes this new method free of activity variation of breast tissues. The threshold value chosen is the key process for the segmentation method. The first valley ill the grey level histogram of the reconstruction image is set as the lower threshold, which works well in clinical application. Results show that attenuation correction for PEMi improves the image quality and the quantitative accuracy of radioactivity distribution determination. Attenuation correction also improves the probability of detecting small and early breast tumors.
Bibliography:breast PET, attenuation correction, region growing, image segmentation
11-5641/O4
GU Xiao-Yue,LI Lin,YIN Peng-Fei, YUN Ming-Ka,CHAI Pei,HUANG Xian-Chao, SUN Xiao-Li,WEI Long（1 Key Laboratory of Nuclear Radiation and Nuclear Energy Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China 2 Beijing Engineering Research Center of Radiographic Techniques and Equipment, Beijing 100049, China）
The Positron Emission Mammography imaging system （PEMi） provides a novel nuclear diagnosis method dedicated for breast imaging. With a better resolution than whole body PET, PEMi can detect millimeter-sized breast tumors. To address the requirement of semi-quantitative analysis with a radiotracer concentration map of the breast, a new attenuation correction method based on a three-dimensional seeded region growing image segmentation （3DSRG-AC） method has been developed. The method gives a 3D connected region as the segmentation result instead of image slices. The continuity property of the segmentation result makes this new method free of activity variation of breast tissues. The threshold value chosen is the key process for the segmentation method. The first valley ill the grey level histogram of the reconstruction image is set as the lower threshold, which works well in clinical application. Results show that attenuation correction for PEMi improves the image quality and the quantitative accuracy of radioactivity distribution determination. Attenuation correction also improves the probability of detecting small and early breast tumors.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1674-1137
0254-3052
DOI:10.1088/1674-1137/39/10/108202