A new indole alkaloidal glucoside from the aerial parts of Clematis terniflora DC

A new indole alkaloidal glucoside together with three known compounds aurantiamide acetate (2), eleutheroside E (3) and 1-O-caffeoyl-β-d-glucopyranoside (4) has been isolated from ethanol extract of the aerial parts of Clematis terniflora DC. On the basis of their spectroscopic and chemical evidence...

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Published inNatural product research Vol. 27; no. 24; pp. 2333 - 2337
Main Authors Li, Wen-Ting, Yang, Bing-Xian, Zhu, Wei, Gong, Ming-Hua, Xu, Xiang-Dong, Lu, Xiang-Hong, Sun, Lian-Li, Tian, Jing-Kui, Zhang, Lin
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 01.12.2013
Subjects
Cell Line, Tumor
Cell Proliferation - drug effects
Clematis - chemistry
Clematis terniflora DC
cytotoxic activity
Glucosides - chemistry
Glucosides - pharmacology
Humans
indole alkaloidal glucoside
Indole Alkaloids - chemistry
Indole Alkaloids - pharmacology
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Components, Aerial - chemistry
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Summary:A new indole alkaloidal glucoside together with three known compounds aurantiamide acetate (2), eleutheroside E (3) and 1-O-caffeoyl-β-d-glucopyranoside (4) has been isolated from ethanol extract of the aerial parts of Clematis terniflora DC. On the basis of their spectroscopic and chemical evidence, the new compound was elucidated as (6-O-β-d-glucopyranosyl-1H-indol-3-yl) carboxylic acid methyl ester (1). Compounds 1 and 3 showed significant cytotoxicity against human ECA-109.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2013.838239