Raman spectroscopy and neuroscience: from fundamental understanding to disease diagnostics and imaging

Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexp...

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Bibliographic Details
Published inAnalyst (London) Vol. 145; no. 1; pp. 3461 - 348
Main Authors Payne, Taylor D, Moody, Amber S, Wood, Avery L, Pimiento, Paula A, Elliott, James C, Sharma, Bhavya
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 18.05.2020
Subjects
Chemical fingerprinting
Diagnostic Imaging - methods
Humans
Neurosciences
Neurosciences - methods
Raman spectroscopy
Spectrum analysis
Spectrum Analysis, Raman - methods
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Summary:Neuroscience would directly benefit from more effective detection techniques, leading to earlier diagnosis of disease. The specificity of Raman spectroscopy is unparalleled, given that a molecular fingerprint is attained for each species. It also allows for label-free detection with relatively inexpensive instrumentation, minimal sample preparation, and rapid sample analysis. This review summarizes Raman spectroscopy-based techniques that have been used to advance the field of neuroscience in recent years. In recent years, Raman spectroscopy-based methods have contributed significantly to the understanding of neurological structure, function, and disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:0003-2654
1364-5528
DOI:10.1039/d0an00083c