Bioactive prenylated xanthones and anthraquinones from Cratoxylum formosum ssp. pruniflorum

• Published in: Tetrahedron Vol. 62; no. 37; pp. 8850 - 8859
• Main Authors: Boonnak, Nawong, Karalai, Chatchanok, Chantrapromma, Suchada, Ponglimanont, Chanita, Fun, Hoong-Kun, Kanjana-Opas, Akkharawit, Laphookhieo, Surat
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 11.09.2006; Elsevier
• Subjects: Anthraquinone; Antibacterial activity; Chemistry; Chemistry, Organic; Cratoxylum formosum ssp. pruniflorum; Cytotoxic activity; Physical Sciences; Pruniflorone; Science & Technology; Xanthone; Pruniflorone; Xanthone; Cratoxylum formosum ssp. pruniflorum; Antibacterial activity; Anthraquinone; Cytotoxic activity; antibacterial activity; anthraquinone; pruniflorone; BARK; Cratoxylum formosum ssp pruniflorum; ANTIBACTERIAL; CHEMISTRY; ROOTS; cytotoxic activity; MEDICINAL-PLANTS; xanthone; EXTRACTIVES
• ISSN: 0040-4020; 1464-5416
• DOI: 10.1016/j.tet.2006.06.003

Ten new compounds ( 1– 10), pruniflorone A–J, together with 21 known compounds ( 11– 31) were isolated from the roots and barks of Cratoxylum formosum ssp. pruniflorum. Their structures were determined by spectroscopic methods. Compounds 1 and 11 were also confirmed by X-ray diffraction data. In addition, antibacterial and cytotoxic activities of the isolates were also evaluated. Nine new prenylated xanthones ( 1– 9) and a new anthraquinone ( 10) were isolated from the roots and barks of Cratoxylum formosum ssp. pruniflorum. In addition, antibacterial and cytotoxic activities of the isolates were also evaluated. [Display omitted]