Prevalence and control of dyslipidemia among persons with diabetes in the United States

• Published in: Diabetes research and clinical practice Vol. 70; no. 3; pp. 263 - 269
• Main Authors: Jacobs, Milagros J., Kleisli, Thomas, Pio, Jose R., Malik, Shaista, L’Italien, Gilbert J., Chen, Roland S., Wong, Nathan D.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.12.2005
• Subjects: Body Mass Index; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Diabetes Complications - blood; Diabetes Complications - epidemiology; Dyslipidemia; Dyslipidemias - blood; Dyslipidemias - epidemiology; Female; HDL-C; Health Surveys; Humans; Male; Middle Aged; Prevalence; Smoking - adverse effects; Societies, Medical; Triglyceride (TG); Triglycerides - blood; United States - epidemiology; United States; HDL-C; Triglyceride (TG); Dyslipidemia
• ISSN: 0168-8227; 1872-8227
• DOI: 10.1016/j.diabres.2005.03.032

: We assessed the prevalence, treatment, and control of dyslipidemia among United States (U.S.) adults with diabetes. : Among 498 adults (projected to 13.4 million) aged ≥18 years with diabetes representative of the U.S. population and surveyed within the cross-sectional National Health and Nutrition Examination Survey 1999–2000, control of lipids was classified according to American Diabetes Association criteria. The extent of low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and triglyceride (TG) control was examined by gender and ethnicity, in comparison to those without diabetes, and according to lipid-lowering treatment. Analyses were weighted to the U.S. population. : Less than one-third of men and only one-fifth of women with diabetes are in control for LDL-C, defined as <2.6 mmol/l (<100 mg/dl); over 70% are not at goal. Over half of men and over two-thirds of women have low levels of HDL-C (≤1.0 mmol/l [<40 mg/dl] in men or ≤1.3 mmol/l [≤50 mg/dl] in women) and over half have elevated levels of triglycerides (≥1.7 mmol/l [150 mg/dl]). Low HDL-C was more common in Caucasians (70.1%) than in Hispanics (58.8%) or African-Americans (41.5%) ( p < 0.001). 28.2% of subjects with diabetes were on lipid-lowering treatment. Control of LDL-C did not differ by treatment status and only 3% of subjects were controlled to target levels for all lipids. : Many persons with diabetes remain uncontrolled for dyslipidemia. Intensified efforts at screening and treatment according to current guidelines are warranted.