Morin ameliorates ovalbumin-induced allergic rhinitis via inhibition of STAT6/SOCS1 and GATA3/T-bet signaling pathway in BALB/c mice

• Published in: Journal of functional foods Vol. 55; pp. 391 - 401
• Main Authors: Liang, Kun, Kandhare, Amit D., Mukherjee-Kandhare, Anwesha A., Bodhankar, Subhash L., Xu, Dingyuan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.04.2019; Elsevier
• Subjects: Allergic rhinitis; GATA3; Morin; Ovalbumin; SOCS1; STAT6; Ovalbumin; Morin; GATA; NLF; GATA3; T-bet; AR; IFN-γ; SOCS1; MLT; TNF-α; Allergic rhinitis; STAT6; IL’s; OVA; STAT-6

[Display omitted] •Allergic rhinitis (AR) was induced in Balb/c mice by using ovalbumin (OVA).•Morin (30 and 1000 mg/kg) significantly attenuated OVA-induced nasal symptoms.•Elevated levels of serum histamine, IgE, IgG1, and β-hexosaminidase decreased by morin.•Morin attenuated nasal lavage fluid IL...