A zirconium-based metal-organic framework sensitized by thioflavin-T for sensitive photoelectrochemical detection of C-reactive protein

Herein, a novel photoelectrochemical (PEC) assay was developed for the sensitive detection of C-reactive protein (CRP) based on a zirconium-based metal-organic framework (PCN-777) as the photoelectric material and thioflavin-T (Th-T) as the effective signal sensitizer coupled with rolling circle amp...

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Published inChemical communications (Cambridge, England) Vol. 55; no. 72; pp. 1772 - 1775
Main Authors Li, Meng-Jie, Wang, Hai-Jun, Yuan, Ruo, Chai, Ya-Qin
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 05.09.2019
Subjects
Biosensors
Electrochemical analysis
Metal-organic frameworks
Optimization
Photoelectricity
Proteins
Reagents
Zirconium
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Summary:Herein, a novel photoelectrochemical (PEC) assay was developed for the sensitive detection of C-reactive protein (CRP) based on a zirconium-based metal-organic framework (PCN-777) as the photoelectric material and thioflavin-T (Th-T) as the effective signal sensitizer coupled with rolling circle amplification (RCA). Herein, a photoelectrochemical (PEC) assay was proposed for sensitive detection of C-reactive protein (CRP) based on zirconium-based metal-organic framework (PCN-777) as the photoelectric material and thioflavine-T (Th-T) as the sensitizer.
Bibliography:10.1039/c9cc05086h
Electronic supplementary information (ESI) available: Materials and reagents, apparatus, PEC measurement, Experimental section, condition optimization and electrochemical characterization of the PEC biosensor. See DOI
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc05086h