Pneumatic tactile stimulus delivery system for studying brain responses evoked by active finger touch with fMRI

• Published in: Journal of neuroscience methods Vol. 397; p. 109938
• Main Authors: Hwang, Seong-Hwan, Park, Doyoung, Paeng, Somang, Lee, Sang Wan, Lee, Sue-Hyun, Kim, Hyoung F.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2023
• Subjects: fMRI; Natural touch; Somatosensory cortex; Tactile perception; Tactile stimuli; Somatosensory cortex; fMRI; Natural touch; Tactile stimuli; Tactile perception; Active touch
• ISSN: 0165-0270; 1872-678X
• DOI: 10.1016/j.jneumeth.2023.109938

Primates use their hands to actively touch objects and collect information. To study tactile information processing, it is important for participants to experience tactile stimuli through active touch while monitoring brain activities. Here, we developed a pneumatic tactile stimulus delivery system (pTDS) that delivers various tactile stimuli on a programmed schedule and allows voluntary finger touches during MRI scanning. The pTDS uses a pneumatic actuator to move tactile stimuli and place them in a finger hole. A photosensor detects the time when an index finger touches a tactile stimulus, enabling the analysis of the touch-elicited brain responses. We examined brain responses while the participants actively touched braille objects presented by the pTDS. BOLD responses during tactile perception were significantly stronger in a finger touch area of the contralateral somatosensory cortex compared with that of visual perception. The pTDS enables MR studies of brain mechanisms for tactile processes through natural finger touch. •We developed a pneumatic tactile stimulus delivery system (pTDS) for MR studies.•The pTDS enables the delivery of various types of tactile stimuli using tactile blocks.•An optical finger sensor allows for precise time detection of the tactile perception.•We demonstrated the feasibility of the pTDS in a human fMRI study.