Simplified antibiotic regimens for neonatal sepsis—AFRINEST – Authors' reply

Mortality is indeed very high in the first week after birth, but the predominant causes of death are preterm birth complications and asphyxia.5 We classified infants with possible serious bacterial infection into three groups on the basis of clinical signs of increasing severity: fast breathing alon...

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Published inThe Lancet (British edition) Vol. 386; no. 10001; p. 1339
Main Authors Esamai, Fabian, Ayede, Adejumoke I, Adejuyigbe, Ebunoluwa A, Tshefu, Antoinette, Wammanda, Robinson D
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 03.10.2015
Elsevier Limited
Subjects
Amoxicillin - administration & dosage
Amoxicillin - therapeutic use
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
Antibiotics
Bacterial infections
Bacterial Infections - drug therapy
Clinical trials
Female
Gentamicins - administration & dosage
Gentamicins - therapeutic use
Humans
Internal Medicine
Male
Mortality
Newborn babies
Penicillin G Procaine - administration & dosage
Penicillin G Procaine - therapeutic use
Referral and Consultation
Sepsis
Tachypnea - etiology
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Summary:Mortality is indeed very high in the first week after birth, but the predominant causes of death are preterm birth complications and asphyxia.5 We classified infants with possible serious bacterial infection into three groups on the basis of clinical signs of increasing severity: fast breathing alone, signs of severe infection (stopped feeding well, severe chest indrawing, fever, hypothermia, and no spontaneous movements), and signs of critical illness such as unconsciousness and convulsions.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(15)00332-3