The impact of endocrine-disrupting chemical exposure in the mammalian hypothalamic-pituitary axis

• Published in: Molecular and cellular endocrinology Vol. 518; p. 110997
• Main Authors: Graceli, Jones B., Dettogni, Raquel S., Merlo, Eduardo, Niño, Oscar, da Costa, Charles S., Zanol, Jordana F., Ríos Morris, Eduardo A., Miranda-Alves, Leandro, Denicol, Anna C.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2020
• Subjects: atrazine; biphenyl; bisphenol A; DDT (pesticide); Endocrine-disrupting chemicals; endocrinology; homeostasis; Hypothalamic-pituitary axis; Hypothalamus; mammals; metabolism; Neuroendocrine action; phthalates; Pituitary; polychlorinated biphenyls; public health; Toxicological effects; tributyltin; Hypothalamic-pituitary axis; Toxicological effects; Neuroendocrine action; Hypothalamus; Endocrine-disrupting chemicals; Pituitary

The hypothalamic-pituitary axis (HP axis) plays a critical and integrative role in the endocrine system control to maintain homeostasis. The HP axis is responsible for the hormonal events necessary to regulate the thyroid, adrenal glands, gonads, somatic growth, among other functions. Endocrine-disr...