Coordination chemistry of thiazoles, isothiazoles and thiadiazoles

• Published in: Coordination chemistry reviews Vol. 308; pp. 32 - 55
• Main Authors: Frija, Luís M.T., Pombeiro, Armando J.L., Kopylovich, Maximilian N.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2016
• Subjects: Isothiazoles; Nitrogen ligands; Sulfur ligands; Thiadiazoles; Thiazoles; Thiadiazoles; Nitrogen ligands; Isothiazoles; Sulfur ligands; Thiazoles
• ISSN: 0010-8545; 1873-3840
• DOI: 10.1016/j.ccr.2015.10.003

This review aims to systematize the existing information on the coordination chemistry of thiazole, isothiazole and thiadiazole polyfunctional ligands and to highlight some perspectives in the synthesis and applications of metal complexes comprising these heterocycles. •Thiazole, isothiazole and thiadiazole-based derivatives as valuable ligands.•Noticeable methods to synthesize thiazole-derived compounds are shortly overviewed.•Main applications of thiazole-based ligands and their metal complexes as catalysts.•Key biological actions of thiadiazole complexes as drugs of different kinds. Thiazole derived compounds have great potential in medicinal- and agro-chemistries, catalysis, cosmetic industry, corrosion protection, light harvesting, production of light-emitting diodes (LEDs), photochromes and molecular switches or nonlinear optical materials. In spite of that, not much attention has been paid to the coordination chemistry of this class of versatile and polyfunctional heterocyclic ligands. This review intends to systematize the existing information in this field and to highlight some perspectives in the synthesis and applications of 1,3-thiazole, isothiazole and thiadiazole metal complexes.