PET/CT Fluoroscopy during PET/CT-Guided Interventions: Initial Experience

• Published in: Journal of vascular and interventional radiology Vol. 34; no. 8; pp. 1319 - 1323
• Main Authors: Jiang, Liwei, Jowkar, Nick, King, Franklin, Plishker, William, Bhagavatula, Sharath K., Levesque, Vincent M., Kapur, Tina, Shyn, Paul B.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2023
• Subjects: Fluoroscopy; Humans; Neoplasms; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography - methods; Tomography, X-Ray Computed - methods; CT; PET
• ISSN: 1051-0443; 1535-7732
• DOI: 10.1016/j.jvir.2023.04.020

This study assessed the feasibility and functionality of the use of a high-speed image fusion technology to generate and display positron emission tomography (PET)/computed tomography (CT) fluoroscopic images during PET/CT-guided tumor ablation procedures. Thirteen patients underwent 14 PET/CT-guided ablations for the treatment of 20 tumors. A Food and Drug Administration–cleared multimodal image fusion platform received images pushed from a scanner, followed by near–real-time, nonrigid image registration. The most recent intraprocedural PET dataset was fused to each single-rotation CT fluoroscopy dataset as it arrived, and the fused images were displayed on an in-room monitor. PET/CT fluoroscopic images were generated and displayed in all procedures and enabled more confident targeting in 3 procedures. The mean lag time from CT fluoroscopic image acquisition to the in-room display of the fused PET/CT fluoroscopic image was 21 seconds ± 8. The registration accuracy was visually satisfactory in 13 of 14 procedures. In conclusion, PET/CT fluoroscopy was feasible and may have the potential to facilitate PET/CT-guided procedures. [Display omitted]