Palladium-catalyzed multicomponent reactions: an overview

This first review on this topic focuses on the developments in the chemistry of Pd-catalyzed multi-component reactions (MCRs). MCRs are generally atom economic, ideal and eco-friendly reactions, and often the final products are generated almost without any by-products. In this review, the developmen...

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Published inOrganic & biomolecular chemistry Vol. 17; no. 35; pp. 848 - 861
Main Authors Saranya, Salim, Rohit, K. R, Radhika, Sankaran, Anilkumar, Gopinathan
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 21.09.2019
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Summary:This first review on this topic focuses on the developments in the chemistry of Pd-catalyzed multi-component reactions (MCRs). MCRs are generally atom economic, ideal and eco-friendly reactions, and often the final products are generated almost without any by-products. In this review, the developments in Pd-catalyzed MCRs are categorized based on the products formed such as acyclic compounds, carbocyclic compounds, heterocyclic compounds and miscellaneous compounds. MCRs have great applications in various fields like medicinal chemistry, combinatorial synthesis, heterocyclic chemistry etc . and this review covers the literature up to 2019. This first review on this topic focuses on the developments in the chemistry of Pd-catalyzed multi-component reactions (MCRs).
Bibliography:Gopinathan Anilkumar was born in Kerala, India and took his Ph.D. in 1996 from Regional Research Laboratory (renamed as the National Institute for Interdisciplinary Science and Technology NIIST-CSIR), Trivandrum with Dr Vijay Nair. He did postdoctoral studies at the University of Nijmegen, The Netherlands (with Professor Binne Zwanenburg), Osaka University, Japan (with Professor Yasuyuki Kita), Temple University, USA (with Professor Franklin A. Davis), Leibniz-Institüt für Organische Katalyse (IfOK), Rostock, Germany (with Professor Matthias Beller) and Leibniz-Institüt für Katalyse an der Universitat (LIKAT), Rostock, Germany (with Professor Matthias Beller). He was a senior scientist at AstraZeneca (India). Currently he is a Professor in Organic Chemistry at the School of Chemical Sciences, Mahatma Gandhi University in Kerala, India. His research interests are in the areas of organic synthesis, medicinal chemistry, heterocycles and catalysis, particularly on ruthenium, iron, zinc, copper, manganese, cobalt and nickel catalyzed reactions. He has published more than 75 papers in peer-reviewed journals, 7 patents and one book chapter. He has received Dr S. Vasudev Award from Govt. of Kerala, India for best research (2016) and the Evonik research proposal competition award (second prize 2016). His h-index is 25.
Salim Saranya was born in 1990 in Kerala, India. She received her B.Sc. and M.Sc. degrees from Christian College, Chengannur in 2012 and 2014 respectively. She qualified the CSIR-UGC National Eligibility Test in 2015 with a research fellowship and currently pursuing her doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University.
K. R. Rohit was born in Kerala, India, in 1992. He obtained his B.Sc. degree from the University of Kerala (Sree Narayana College, Cherthala) in 2013 and his M.Sc. degree from the School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala in 2015. He also completed his M. Phil degree from the School of Chemical Sciences in 2017 under the guidance of Dr G. Anilkumar. He has qualified the CSIR-UGC National Eligibility Test (NET) 2016 with a research fellowship and currently pursuing his doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University.
S. Radhika was born in Thodupuzha, Kerala, India, in 1994. She obtained her B.Sc. degree in 2014 and M.Sc. degree in 2016 from St Joseph's College, Moolamattom (Mahatma Gandhi University). She secured second rank in M.Sc. Pure Chemistry Examination 2016 conducted by Mahatma Gandhi University, Kottayam. She cleared the UGC-National Eligibility Test (NET) in 2017. After qualifying for the KSCSTE fellowship, she is currently doing her doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University.
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ISSN:1477-0520
1477-0539
DOI:10.1039/c9ob01538h