Chemical-Induced Naive Pluripotency

The capacity to harness the properties of pluripotent stem cells has a wide-reaching impact on regenerative medicine, drug discovery, and also basic science. Two recent publications by Ursu et al. and Illich et al. demonstrate that inhibition of a CK1 isoform efficiently induces naive pluripotency i...

Full description

Saved in:
Bibliographic Details
Published inCell chemical biology Vol. 23; no. 5; pp. 532 - 534
Main Authors Russell, Angela J., Silpa, Laurence
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 19.05.2016
Online AccessGet full text

Cover

More Information
Summary:The capacity to harness the properties of pluripotent stem cells has a wide-reaching impact on regenerative medicine, drug discovery, and also basic science. Two recent publications by Ursu et al. and Illich et al. demonstrate that inhibition of a CK1 isoform efficiently induces naive pluripotency in epiblast stem cells. The capacity to harness the properties of pluripotent stem cells has a wide-reaching impact on regenerative medicine, drug discovery, and also basic science. Two recent publications by Ursu et al. and Illich et al. demonstrate that inhibition of a CK1 isoform efficiently induces naive pluripotency in epiblast stem cells.
ISSN:2451-9456
2451-9448
2451-9456
DOI:10.1016/j.chembiol.2016.05.002