TRIPLE-PHASE HELICAL COMPUTED TOMOGRAPHY IN DOGS WITH HEPATIC MASSES

• Published in: Veterinary radiology & ultrasound Vol. 55; no. 1; pp. 7 - 15
• Main Authors: Kutara, Kenji, Seki, Mamiko, Ishikawa, Chieko, Sakai, Manabu, Kagawa, Yumiko, Iida, Gentoku, Ishigaki, Kumiko, Teshima, Kenji, Edamura, Kazuya, Nakayama, Tomohiro, Asano, Kazushi
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.01.2014
• Subjects: Animals; Carcinoma, Hepatocellular - diagnostic imaging; Carcinoma, Hepatocellular - veterinary; computed tomography; dog; Dog Diseases - diagnostic imaging; Dogs; Female; hepatic metastatic tumor; hepatocellular carcinoma; Hyperplasia - diagnostic imaging; Hyperplasia - veterinary; Liver - diagnostic imaging; Liver - pathology; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - veterinary; Male; nodular hyperplasia; Tomography, Spiral Computed - veterinary; computed tomography; nodular hyperplasia; hepatic metastatic tumor; dog; hepatocellular carcinoma
• ISSN: 1058-8183; 1740-8261
• DOI: 10.1111/vru.12099

The purpose of this study was to determine the utility of triple‐phase helical computed tomography (CT) for differentiating canine hepatic masses. Seventy dogs with hepatic masses underwent triple‐phase CT followed by surgical removal of the hepatic masses. Triple‐phase helical CT scans for each dog included precontrast, arterial phase, portal venous phase, and delayed phase studies. The removed hepatic masses were histopathologically classified as hepatocellular carcinoma (n = 47), nodular hyperplasia (n = 14), and hepatic metastatic tumors (n = 9) in dogs. Of the 47 hepatocellular carcinomas, the most common CT findings included a heterogeneous pattern with hyper‐, iso‐, and hypoenhancement in both the arterial and portal venous phases (40/47, 85.1%). Of the 14 nodular hyperplasias, the most common CT findings were a homogeneous pattern with hyper‐ and isoenhancement in both the portal venous and delayed phases (13/14, 92.9%). Of nine hepatic metastatic tumors, the most common CT findings included a homogeneous hypoenhancement pattern in both the arterial and portal venous phases (8/9, 88.9%). In addition, 5 (55.6%) showed homogeneous hypoenhancement patterns in the delayed phase. Findings from our study indicated that triple‐phase CT is a useful tool for preoperative differentiation of hepatocellular carcinoma, nodular hyperplasia, and hepatic metastatic tumors in dogs.