A novel method for analysis of TOMROP data
Purpose To develop an efficient method for extracting maps of the corrected T1 from images generated using the T One by Multiple Read Out Pulses (TOMROP) sequence. Materials and Methods An expression is developed for the true T1 in terms of the parameters from a three‐parameter fit of the TOMROP dat...
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Published in | Journal of magnetic resonance imaging Vol. 19; no. 4; pp. 508 - 512 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.04.2004
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Subjects | |
Online Access | Get full text |
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Summary: | Purpose
To develop an efficient method for extracting maps of the corrected T1 from images generated using the T One by Multiple Read Out Pulses (TOMROP) sequence.
Materials and Methods
An expression is developed for the true T1 in terms of the parameters from a three‐parameter fit of the TOMROP data. Solutions of gadodiamide in normal saline with concentrations of 0.0, 0.06, 0.11, 0.23, 0.46, and 0.91 mM were prepared and T1 measurements were performed using both the inversion recovery (IR) and the TOMROP methods. The TOMROP data were analyzed using the proposed technique and the results compared to those from the IR measurements.
Results
The T1 estimates generated from the TOMROP data using the proposed method were consistent with the IR results. However, systematic errors were observed in the T1 estimates when the repetition time was not sufficient for full recovery of axial magnetization. Relaxation times determined using the proposed method were within 1% of the spectroscopiclly determined values for T1 values in the range of 0.28–2.8 seconds when a suitable delay was employed.
Conclusion
The proposed method of analysis was found to yield accurate T1 estimates when the assumptions used in the analysis were not violated. J. Magn. Reson. Imaging 2004;19:508–512. © 2004 Wiley‐Liss, Inc. |
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Bibliography: | istex:19FD5D178DD43888842802D4FA5A8C529EEAFB75 ArticleID:JMRI20027 ark:/67375/WNG-WXZ1449J-M NIH - No. RO1-NS-37844 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1053-1807 1522-2586 |
DOI: | 10.1002/jmri.20027 |