Immunological principles regulating immunomodulation with biomaterials

The immune system has evolved to recognize and eliminate pathogens; this recognition relies on the identification of structural molecular patterns within unique tissue microenvironments. Therefore, bioengineers can harness these immunological cues to design materials that modulate innate and adaptiv...

Full description

Saved in:
Bibliographic Details
Published inActa biomaterialia Vol. 10; no. 4; pp. 1720 - 1727
Main Authors Khan, Tarik A., Reddy, Sai T.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.2014
Subjects
Adaptive Immunity - drug effects
Adjuvants
Animals
Biocompatible Materials - pharmacology
Humans
Immunity - drug effects
Immunoengineering
Immunology
Immunomodulation - drug effects
Monitoring, Immunologic
Vaccine delivery
Adjuvants
Immunology
Vaccine delivery
Immunoengineering
Online AccessGet full text

Cover

More Information
Summary:The immune system has evolved to recognize and eliminate pathogens; this recognition relies on the identification of structural molecular patterns within unique tissue microenvironments. Therefore, bioengineers can harness these immunological cues to design materials that modulate innate and adaptive immunity in a controlled manner. This review acts as an immunology primer by focusing on the basic molecular and cellular immunology principles governing immunomodulation with biomaterials.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1742-7061
1878-7568
DOI:10.1016/j.actbio.2013.12.011