Anticancer activity of seaweeds

•Anti-cancer activity of seaweeds has been probed in numerous studies.•Total growth inhibition is a good parameter to evaluate seaweeds’ activity.•We propose the cumulative dose to estimate algae anti-cancer in vivo effects. Cancer is a major health problem worldwide and still lacks fully effective...

Full description

Saved in:
Bibliographic Details
Published inDrug discovery today Vol. 23; no. 2; pp. 434 - 447
Main Authors Gutiérrez-Rodríguez, Anllely G., Juárez-Portilla, Claudia, Olivares-Bañuelos, Tatiana, Zepeda, Rossana C.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.02.2018
Online AccessGet full text

Cover

More Information
Summary:•Anti-cancer activity of seaweeds has been probed in numerous studies.•Total growth inhibition is a good parameter to evaluate seaweeds’ activity.•We propose the cumulative dose to estimate algae anti-cancer in vivo effects. Cancer is a major health problem worldwide and still lacks fully effective treatments. Therefore, alternative therapies, using natural products, have been proposed. Marine algae are an important component of the marine environment, with high biodiversity, and contain a huge number of functional compounds, including terpenes, polyphenols, phlorotannins, and polysaccharides, among others. These compounds have complex structures that have shown several biological activities, including anticancer activity, using in vitro and in vivo models. Moreover, seaweed-derived compounds target important molecules that regulate cancer processes. Here, we review our current understanding of the anticancer activity of seaweeds.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1359-6446
1878-5832
DOI:10.1016/j.drudis.2017.10.019