Highly sensitive chemiluminescence sensing system for organophosphates using mimic LDH supported ZIF-8 nanocomposite

• Published in: Sensors and actuators. B, Chemical Vol. 284; pp. 220 - 227
• Main Authors: Bagheri, Nafiseh, Khataee, Alireza, Hassanzadeh, Javad, Samaei, Lale
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.04.2019; Elsevier Science Ltd
• Subjects: Catalysis; Change detection; Chemical synthesis; Chemiluminescence; Diazinon; Emission analysis; Hydrogen peroxide; Hydroxides; Layered double hydroxides; Metal-organic frameworks; Nanocomposite; Nanocomposites; Organic chemistry; Organophosphates; Peroxidase; Poisons; Reproducibility; Rhodamine; Selectivity; Nanocomposite; Chemiluminescence; Metal-organic frameworks; Diazinon; Layered double hydroxides
• ISSN: 0925-4005; 1873-3077
• DOI: 10.1016/j.snb.2018.12.147

[Display omitted] •Synthesis of layered double hydroxides supported ZIF-8 nanocomposite (LDH@ZIF-8).•Promoting effect of LDH@ZIF-8 on rhodamine B-H2O2 chemiluminescence (CL) system.•Highly sensitive detection of H2O2 by enhanced CL system with a LOD of 0.045 nM.•Developing a reliable assay for diazinon which can hinder enzymatic H2O2 production. Developing a new detection system for reliable recognition of threatening organophosphate poisons (OPs) is a challenging subject for analysts to control their undesirable effects. Here, a sensitive analytical assay for OPs was reported based on the high mimetic behavior of layered double hydroxides supported ZIF-8 nanocomposite (LDH@ZIF-8). The well-known inhibiting effect of OP analytes on the enzymatic activity of acetylcholinesterase (AChE) was exerted to gain a suitable selectivity. Following that, efficient chemiluminescence (CL) system assisted by LDH@ZIF-8 was employed to monitor the variation in the amount of produced H2O2. It is found that the synthesized LDH@ZIF-8 possess a high effective peroxidase-like activity and can remarkably enhance the emission of the ultra-weak rhodamine B (RhoB)-H2O2 CL reaction. More studied was done using fluorometric to ratify the mimetic properties of LDH@ZIF-8 nanocomposite. The high catalytic effect of developed nanocomposite assured the high efficacy of the CL system to detect the small changes in H2O2 concentration, resulting in a high sensitivity in the detection of OPs. The low-priced and simple synthesized LDH@ZIF-8 catalyst, as well as a simple and easy-to-use CL system can be beneficial in the development of an on-site and portable detection tools. A wide linear range of 0.5–300 nM was achieved for the determination of diazinon (as a model OP), and the detection limit was as low as 0.22 nM. The method showed high reproducibility and was reassured by its application for the analysis of environmental samples.