Host Defence Against Candida albicans and the Role of Pattern-recognition Receptors

Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-...

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Published inActa dermato-venereologica Vol. 92; no. 3; pp. 291 - 298
Main Authors GAUGLITZ, Gerd G, CALLENBERG, Helene, WEINDL, Günther, KORTING, Hans C
Format Journal Article
LanguageEnglish
Published Uppsala Acta dermato-venereologica 01.01.2012
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Summary:Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors responsible for recognition of special structures of C. albicans, which are known to activate intracellular signals that finally lead to directed and efficient host defence.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0001-5555
1651-2057
DOI:10.2340/00015555-1250