Default mode network-associated intrinsic connectivity relates to individual learnability differences in errorless and trial-and-error learning

• Published in: Applied neuropsychology. Adult Vol. ahead-of-print; no. ahead-of-print; pp. 1 - 9
• Main Authors: Yamashita, Madoka, Shimokawa, Tetsuya, Tanemura, Rumi
• Format: Journal Article
• Language: English
• Published: United States Routledge 23.08.2022
• Subjects: Cognitive rehabilitation; default mode network; errorless learning; functional magnetic resonance imaging; trial-and-error learning; Cognitive rehabilitation; trial-and-error learning; default mode network; errorless learning; functional magnetic resonance imaging
• ISSN: 2327-9095; 2327-9109
• DOI: 10.1080/23279095.2022.2111518

The intrinsic functional network architecture accounts for task-evoked brain activity changes and variabilities in cognitive performance. Relationships between the intrinsic functional network architecture and task performance or learning ability have been previously reported. However, the relationships between learning benefits and the characteristics of intrinsic functional network architecture for different types of learning methods remain unclear. In this study, we used graph theoretical analysis to examine the relationships between intrinsic functional network connectivity and learning benefits in two well-known learning methods in the field of cognitive rehabilitation-errorless learning (EL learning) and trial-and-error learning (T&E learning). We focused on the default mode network (DMN) as a task-relevant network, which can differentiate between EL and T&E learning and was found to be more important for T&E learning in a previous study. Participants performed a color-name association task with both learning methods. The graph metrics used were within-network connectivity and efficiency for the DMN. Within-DMN connectivity and DMN efficiency showed a significantly weak positive correlation with T&E scores but not with EL scores. These findings show that the intrinsic integration strength within the DMN relates to individuals' learnability through the T&E method.