Microbiome and cancer immunotherapy

Immunomodulation has become a promising and growing field of cancer research. Compelling results from a variety of studies provide strong evidence for the importance of commensal bacteria on oncologic outcomes and response to antitumor immunotherapies. The gut microbiome has emerged as a new prognos...

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Bibliographic Details
Published inCurrent opinion in biotechnology Vol. 65; pp. 114 - 117
Main Authors Chilakapati, Shanmuga Reddy, Ricciuti, Jason, Zsiros, Emese
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.10.2020
Subjects
Gastrointestinal Microbiome
Humans
Immunity
Immunotherapy
Microbiota
Neoplasms - therapy
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Summary:Immunomodulation has become a promising and growing field of cancer research. Compelling results from a variety of studies provide strong evidence for the importance of commensal bacteria on oncologic outcomes and response to antitumor immunotherapies. The gut microbiome has emerged as a new prognostic biomarker and a potential therapeutic target to enhance the efficacy of immunotherapy.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0958-1669
1879-0429
DOI:10.1016/j.copbio.2020.02.007