Green synthesized Cobalt oxide nanoparticles using Curcuma longa for anti-oxidant, antimicrobial, dye degradation and anti-cancer property

• Published in: Environmental research Vol. 236; no. Pt 1; p. 116747
• Main Authors: Shanmuganathan, Rajasree, Sathiyavimal, Selvam, Hoang Le, Quynh, M. Al-Ansari, Mysoon, A. Al-Humaid, Latifah, Jhanani, G.K., Lee, Jintae, Barathi, Selvaraj
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.11.2023
• Subjects: Anticancer activity; Antimicrobial activity; Antioxidants; Cobalt oxide nanoparticles; Curcuma longa; Dye degradation; Antioxidants; Dye degradation; Antimicrobial activity; Curcuma longa; Cobalt oxide nanoparticles; Anticancer activity
• ISSN: 0013-9351; 1096-0953
• DOI: 10.1016/j.envres.2023.116747

In the present study, cobalt oxide nanoparticles have been synthesized using the root extract of Curcuma longa in a manner that is both environmentally friendly and economical. Initially, the synthesized nanoparticles were characterized using a UV–Vis spectroscopy analysis, in which plasma resonance at 345 nm was observed, which confirmed that CL-Cobalt oxide nanoparticles were synthesized. While FTIR analysis showed a peak at 597.37 cm−1 indicating Co–O stretching vibration. In addition, DLS, SEM and XRD analyses confirmed the synthesis of polydispersed (average size distribution of 97.5 ± 35.1 nm), cubic phase structure, and spherical-shaped CL-Cobalt oxide nanoparticles. CL-Cobalt oxide nanoparticles synthesized from green materials showed antioxidant and antimicrobial properties. CL-Cobalt oxide nanoparticles exhibited antibacterial activity against Gram negative (Klebsiella pneumoniae and Escherichia coli) and Gram positive bacteria (Bacillus subtilis, Staphylococcus aureus), while CL-Cobalt oxide nanoparticles additionally displayed significant antifungal activity against Aspergillus niger. CL-Cobalt oxide also showed application in a bioremediation perspective by showing strong photocatalytic degradation of methyl red, methyl orange and methyl blue dye. In addition, CL-Cobalt oxide also demonstrated anticancer activity against MDA-MB-468 cancer cell lines with an IC50 value of 150.8 μg/ml. Therefore, this is the first and foremost report on CL-Cobalt oxide nanoparticles synthesized using Curcuma longa showing antioxidant, antibacterial, antifungal, dye degradation and anticancer applications. •Greenly synthesized CL-Cobalt oxide nanoparticles was done with root extract of C. longa.•Different characterization studies of synthesized nanoparticles were discussed.•Activities like antioxidant, antimicrobial, photocatalytic activity under solar irradiation.