A case of levetiracetam induced bullous pemphigoid

Bullous pemphigoid is a chronic, acquired autoimmune skin disease. Certain drugs such as furosemide, penicillins, sulfonamides, ciprofloxacins, penicillamines, angiotensin converting enzyme inhibitors, chloroquine, and phenacetin were reported to cause bullous pemphigoid. This is a case report of a...

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Published inCutaneous and ocular toxicology Vol. 32; no. 2; p. 176
Main Authors Karadag, Ayse Serap, Bilgili, Serap Gunes, Calka, Omer, Onder, Sevda, Kosem, Mustafa, Burakgazi-Dalkilic, Evren
Format Journal Article
LanguageEnglish
Published England 01.06.2013
Subjects
Aged
Anticonvulsants - adverse effects
Complement System Proteins - immunology
Female
Humans
Immunoglobulin G - immunology
Pemphigoid, Bullous - chemically induced
Pemphigoid, Bullous - immunology
Pemphigoid, Bullous - pathology
Piracetam - adverse effects
Piracetam - analogs & derivatives
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Summary:Bullous pemphigoid is a chronic, acquired autoimmune skin disease. Certain drugs such as furosemide, penicillins, sulfonamides, ciprofloxacins, penicillamines, angiotensin converting enzyme inhibitors, chloroquine, and phenacetin were reported to cause bullous pemphigoid. This is a case report of a 70-year-old female, who presented with the formation of diffuse cutaneous blister in month after starting to use levetiracetam. Dermatological exam and histopathological findings were consistent with bullous pemphigoid. To the best of our knowledge this is the first case of bullous pemphigoid in the literature associated with levetiracetam use.
ISSN:1556-9535
DOI:10.3109/15569527.2012.725444