Laser photothermolysis of biological tissues by using plasmon-resonance particles

The spatial temperature distribution in biological tissues upon interaction of laser radiation with plasmon-resonance nanoparticles is simulated numerically. Experimental thermograms of model objects and real biological tissues are obtained in vivo for different localisation depths of nanoparticles...

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Bibliographic Details
Published inQuantum electronics (Woodbury, N.Y.) Vol. 38; no. 6; pp. 536 - 542
Main Authors Maksimova, I L, Akchurin, G G, Terentyuk, G S, Khlebtsov, B N, Ermolaev, I A, Skaptsov, A A, Revzina, E M, Tuchin, V V, Khlebtsov, N G
Format Journal Article
LanguageEnglish
Published United States IOP Publishing 30.06.2008
Subjects
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
HADRONS
IN VIVO
INTERACTIONS
IRRADIATION
LASER RADIATION
LASERS
NANOSCIENCE AND NANOTECHNOLOGY
NANOSTRUCTURES
RADIATION EFFECTS
RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS
RADIATIONS
RESONANCE PARTICLES
SIMULATION
TEMPERATURE DISTRIBUTION
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Summary:The spatial temperature distribution in biological tissues upon interaction of laser radiation with plasmon-resonance nanoparticles is simulated numerically. Experimental thermograms of model objects and real biological tissues are obtained in vivo for different localisation depths of nanoparticles in different irradiation regimes. The results obtained in the study can be used for the development of methods of laser photothermolysis of malignant tumours. (special issue devoted to application of laser technologies in biophotonics and biomedical studies)
ISSN:1063-7818
1468-4799
DOI:10.1070/QE2008v038n06ABEH013863