NAD+ in sulfur mustard toxicity

•Sulfur mustard (SM) and its derivatives are potent toxicants.•The molecular mechanisms behind SM-induced toxicity are not fully understood.•The paper discusses the role of NAD + in SM toxicity.•The beneficial effects of NAD + precursors in SM toxicity are also discussed. Sulfur mustard (SM) is a to...

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Published inToxicology letters Vol. 324; pp. 95 - 103
Main Authors Ruszkiewicz, Joanna A., Bürkle, Alexander, Mangerich, Aswin
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.05.2020
Subjects
Animals
Chemical Warfare Agents - toxicity
Cytotoxicity
Dietary Supplements
Humans
Mustard Gas - toxicity
NAD
NAD - administration & dosage
NAD - physiology
Niacinamide - administration & dosage
Nicotinamide adenine dinucleotide
Oxidative Stress - drug effects
PARP
Poly(ADP-ribose) Polymerases - metabolism
Reactive Nitrogen Species - metabolism
Sirtuins
Sirtuins - antagonists & inhibitors
Sulfur mustard
NAD
Sirtuins
Nicotinamide adenine dinucleotide
Cytotoxicity
PARP
Sulfur mustard
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Abstract •Sulfur mustard (SM) and its derivatives are potent toxicants.•The molecular mechanisms behind SM-induced toxicity are not fully understood.•The paper discusses the role of NAD + in SM toxicity.•The beneficial effects of NAD + precursors in SM toxicity are also discussed. Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully understood and no antidote or effective therapy against SM exists. Both, the risk of SM release in asymmetric conflicts or terrorist attacks and the usage of SM-derived nitrogen mustards as cancer chemotherapeutics, render the mechanisms of mustard-induced toxicity a highly relevant research subject. Herein, we review a central role of the abundant cellular molecule nicotinamide adenine dinucleotide (NAD+) in molecular mechanisms underlying SM toxicity. We also discuss the potential beneficial effects of NAD+ precursors in counteracting SM-induced damage.
AbstractList Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully understood and no antidote or effective therapy against SM exists. Both, the risk of SM release in asymmetric conflicts or terrorist attacks and the usage of SM-derived nitrogen mustards as cancer chemotherapeutics, render the mechanisms of mustard-induced toxicity a highly relevant research subject. Herein, we review a central role of the abundant cellular molecule nicotinamide adenine dinucleotide (NAD ) in molecular mechanisms underlying SM toxicity. We also discuss the potential beneficial effects of NAD precursors in counteracting SM-induced damage.
Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully understood and no antidote or effective therapy against SM exists. Both, the risk of SM release in asymmetric conflicts or terrorist attacks and the usage of SM-derived nitrogen mustards as cancer chemotherapeutics, render the mechanisms of mustard-induced toxicity a highly relevant research subject. Herein, we review a central role of the abundant cellular molecule nicotinamide adenine dinucleotide (NAD+) in molecular mechanisms underlying SM toxicity. We also discuss the potential beneficial effects of NAD+ precursors in counteracting SM-induced damage.Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully understood and no antidote or effective therapy against SM exists. Both, the risk of SM release in asymmetric conflicts or terrorist attacks and the usage of SM-derived nitrogen mustards as cancer chemotherapeutics, render the mechanisms of mustard-induced toxicity a highly relevant research subject. Herein, we review a central role of the abundant cellular molecule nicotinamide adenine dinucleotide (NAD+) in molecular mechanisms underlying SM toxicity. We also discuss the potential beneficial effects of NAD+ precursors in counteracting SM-induced damage.
•Sulfur mustard (SM) and its derivatives are potent toxicants.•The molecular mechanisms behind SM-induced toxicity are not fully understood.•The paper discusses the role of NAD + in SM toxicity.•The beneficial effects of NAD + precursors in SM toxicity are also discussed. Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully understood and no antidote or effective therapy against SM exists. Both, the risk of SM release in asymmetric conflicts or terrorist attacks and the usage of SM-derived nitrogen mustards as cancer chemotherapeutics, render the mechanisms of mustard-induced toxicity a highly relevant research subject. Herein, we review a central role of the abundant cellular molecule nicotinamide adenine dinucleotide (NAD+) in molecular mechanisms underlying SM toxicity. We also discuss the potential beneficial effects of NAD+ precursors in counteracting SM-induced damage.
Author Ruszkiewicz, Joanna A.
Bürkle, Alexander
Mangerich, Aswin
Author_xml – sequence: 1
  givenname: Joanna A.
  surname: Ruszkiewicz
  fullname: Ruszkiewicz, Joanna A.
  email: joanna.ruszkiewicz@uni-konstanz.de
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  givenname: Alexander
  orcidid: 0000-0003-1069-2656
  surname: Bürkle
  fullname: Bürkle, Alexander
  email: alexander.buerkle@uni-konstanz.de
– sequence: 3
  givenname: Aswin
  orcidid: 0000-0001-9742-2338
  surname: Mangerich
  fullname: Mangerich, Aswin
  email: aswin.mangerich@uni-konstanz.de, amang@mit.edu
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32017979$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1006/taap.1999.8634
10.1016/0041-008X(85)90123-1
10.1016/0041-008X(91)90307-Z
10.3109/19390211.2014.952865
10.1016/j.mam.2012.12.010
10.1016/j.taap.2015.03.009
10.1016/j.mrfmmm.2011.11.008
10.3109/08958378.2014.920439
10.1007/s00204-016-1873-x
10.1016/j.toxlet.2015.04.006
10.1016/j.dnarep.2019.06.009
10.1042/BST20180417
10.3389/fphar.2018.01453
10.3109/10915819609048334
10.3109/01480545.2015.1122033
10.1046/j.0022-202x.2001.01578.x
10.1038/s41598-017-09648-6
10.1016/j.cmet.2015.05.023
10.3109/15563651003623297
10.1016/j.taap.2011.10.010
10.1016/j.taap.2016.05.014
10.1016/j.trecan.2017.06.001
10.1016/j.cytogfr.2017.11.001
10.1089/ars.2012.5082
10.1016/j.bbadis.2017.04.024
10.1007/978-1-4939-8588-3_1
10.1016/j.freeradbiomed.2019.07.017
10.1016/j.cbi.2013.06.010
10.1080/15569527.2018.1495230
10.1152/ajpheart.00409.2017
10.3109/01913129009076129
10.1007/BF00148168
10.1002/jcb.25892
10.2174/092986707780597998
10.1016/0041-008X(92)90119-D
10.1080/15376516.2017.1320695
10.1016/j.tox.2008.08.011
10.1038/nrm.2017.53
10.1177/1479972307087191
10.1016/S0009-2797(00)00209-X
10.1002/1099-1263(200012)20:1+<::AID-JAT664>3.3.CO;2-D
10.1089/ars.2017.7216
10.1016/j.tox.2008.06.002
10.1007/s00204-014-1370-z
10.1016/j.lfs.2019.03.064
10.1093/nar/gkx1205
10.1016/0378-4274(87)90263-3
10.1016/j.toxlet.2019.03.012
10.1016/j.mam.2013.01.004
10.1007/s00204-007-0265-7
10.1016/S0009-2797(96)03692-7
10.1016/0887-2333(92)90038-S
10.1016/j.bcp.2014.06.021
10.1080/15287399409531890
10.3389/fimmu.2019.01187
10.1155/2012/321653
10.1016/j.toxlet.2015.09.002
10.1002/jat.2550150213
10.3816/CLC.2010.n.002
10.1128/AEM.00630-11
10.3109/01480545.2010.505238
10.7717/peerj.1890
10.1016/j.taap.2010.04.001
10.1080/15569527.2018.1464018
10.1007/s00204-017-2086-7
10.1016/j.cmet.2018.02.011
10.1016/j.cbi.2018.03.011
10.1101/gad.183509.111
10.1016/j.taap.2019.01.013
10.1016/j.taap.2010.07.018
10.1046/j.1523-1747.1998.00250.x
10.1093/toxsci/54.1.212
10.1016/j.celrep.2018.07.038
10.1016/j.toxlet.2017.11.024
10.1021/jz302015s
10.1016/j.tox.2009.01.019
10.15252/embr.201846263
10.1111/bcpt.12666
10.1007/BF00755605
10.1007/s00204-013-1111-8
10.1016/j.tiv.2004.01.009
10.3389/fendo.2018.00783
10.1016/j.toxlet.2015.08.1105
10.1038/sj.jid.5701234
10.1016/S0887-2333(00)00005-9
10.1093/toxsci/58.1.153
10.3109/08958378.2015.1092184
10.1097/j.pain.0000000000000862
10.1016/j.toxlet.2015.09.010
10.1016/j.bbapap.2014.12.015
10.1177/0748233707083541
10.1016/j.toxlet.2017.09.003
10.1089/ars.2017.7290
10.1146/annurev.nutr.28.061807.155443
10.3109/01480545.2012.710629
10.1080/15569520701863696
10.1016/S0891-5849(03)00439-8
10.1016/S0021-9258(18)64789-1
10.1016/j.ajpath.2010.12.004
10.1007/s002040050383
10.4331/wjbc.v5.i1.58
10.3109/08923973.2011.638306
10.5812/ircmj.15129
10.1080/08958378.2018.1545809
10.1016/j.taap.2011.06.012
10.1016/0300-483X(92)90109-R
10.1007/s00408-009-9178-y
10.1038/ncomms12948
10.1073/pnas.1417290112
10.1038/nrc1587
10.1016/j.tox.2008.08.025
10.1016/j.cmet.2012.04.022
10.1089/ars.2017.7269
10.1002/jat.1134
10.1007/BF02443803
10.1007/s00204-018-2324-7
10.1007/s00018-019-03366-0
10.1016/j.toxrep.2016.03.007
10.1016/j.cmet.2017.11.002
10.3109/15569527.2015.1076436
10.1074/jbc.RA118.005772
10.1186/1478-811X-8-31
10.3109/00498259509061842
10.1016/j.cellsig.2013.06.007
10.3390/ijms14023834
10.1042/bj1030514
10.1016/j.etap.2017.06.016
10.1089/109793300440695
10.1016/j.toxlet.2017.11.005
10.1016/j.bbamcr.2017.05.010
10.1016/j.dnarep.2017.02.001
10.1093/toxsci/kfv226
10.1016/j.bcp.2010.06.010
10.1016/j.cbi.2014.05.015
10.1038/nature25143
10.1016/j.freeradbiomed.2009.09.011
10.1016/j.tox.2006.06.019
10.1016/0272-0590(91)90203-G
10.1016/0041-008X(92)90223-F
10.1111/j.1749-6632.2010.05605.x
10.1016/j.etap.2016.06.001
10.1080/08958378.2018.1558316
10.1073/pnas.1718819115
10.1016/j.cell.2007.07.035
10.1016/0009-2797(94)90005-1
10.1002/jcb.26247
10.1111/j.1742-7843.2010.00623.x
10.1016/0041-008X(89)90143-9
10.1007/s00018-017-2527-8
10.1038/s41598-019-46120-z
10.1007/BF00260563
10.3109/15569527.2013.794818
10.1074/jbc.M413296200
10.1016/0009-2797(94)03596-Z
10.1080/01902148.2016.1194501
10.1016/j.lfs.2006.11.052
10.1124/jpet.108.145037
10.1016/j.tox.2006.11.048
10.1016/j.toxlet.2009.04.012
10.1016/j.taap.2004.06.020
10.1016/0272-0590(85)90123-X
10.1016/j.toxlet.2017.12.014
10.1016/0300-483X(93)90116-A
10.1080/08923973.2018.1460754
10.1016/j.redox.2018.04.006
10.3390/cancers11070955
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Keywords NAD
Sirtuins
Nicotinamide adenine dinucleotide
Cytotoxicity
PARP
Sulfur mustard
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References Sun, Yang, Meng, Xu, Lin, Chen, Zhao, Xiao (bib0730) 2018; 286
Ludlum, Papirmeister (bib0380) 1986; 38
Hwang, Song (bib0240) 2017; 74
Ries, Popp, Egea, Kehe, Jochum (bib0620) 2009; 263
Salminen, Kaarniranta, Kauppinen (bib0640) 2013; 14
Rajman, Chwalek, Sinclair (bib0595) 2018; 27
Weidele, Beneke, Burkle (bib0800) 2017; 52
Gross, Meier, Papirmeister, Brinkley, Johnson (bib0195) 1985; 81
Panahi, Ghanei, Hajhashemi, Sahebkar (bib0525) 2016; 13
Ghanei, Harandi (bib0170) 2010; 11
Graham, Chilcott, Rice, Milner, Hurst, Maliner (bib0190) 2005; 4
Kulkarni, Donepudi, Xu, Wei, Cheng, Driscoll, Johnson, Johnson, Li, Slitt (bib0325) 2014; 20
Wagner, Lang, Popp, Schmidt, Thiermann, Steinritz, Kehe (bib0780) 2019; 312
Hamity, White, Walder, Schmidt, Brenner, Hammond (bib0210) 2017; 158
Bogan, Brenner (bib0065) 2008; 28
Chaitanya, Steven, Babu (bib0100) 2010; 8
Malaviya, Sunil, Cervelli, Anderson, Holmes, Conti, Gordon, Laskin, Laskin (bib0395) 2010; 248
Plahovinsak, Buccellato, Reid, Graham (bib0560) 2016; 35
Papirmeister, Gross, Meier, Petrali, Johnson (bib0540) 1985; 5
Purohit, Simeone, Lyssiotis (bib0585) 2019; 11
Zhang, Mei, Wang, Liu, Jiang, Zhou, Zhang (bib0860) 2017; 55
Jafari, Ghanei (bib0255) 2010; 48
Mishra, Kowluru (bib0475) 2017; 1863
Aguilar-Quesada, Munoz-Gamez, Martin-Oliva, Peralta-Leal, Quiles-Perez, Rodriguez-Vargas, Ruiz de Almodovar, Conde, Ruiz-Extremera, Oliver (bib0010) 2007; 14
Canto, Sauve, Bai (bib0090) 2013; 34
Mei, Zhang, Jiang, Cheng, Liu, Zheng, Zhou, Zhang (bib0430) 2014; 1
Mol, van de Ruit, Kluivers (bib0490) 1989; 98
Jiang, Zhou, Wang, Pang, Huang, Ye, Wan, Qiu, Pei, Jiang, Huang, Yang, Ling, Li, Zhang, Yang (bib0265) 2019; 225
Stromland, Niere, Nikiforov, VanLinden, Heiland, Ziegler (bib0725) 2019; 47
Rappeneau, Baeza-Squiban, Marano, Calvet (bib0605) 2000; 58
Korkmaz, Kunak, Paredes, Yaren, Tan, Reiter (bib0320) 2008; 29
Panahi, Rajaee, Sahebkar (bib0530) 2017; 118
Kehe, Raithel, Kreppel, Jochum, Worek, Thiermann (bib0295) 2008; 82
Virág (bib0775) 2006
Shohrati, Ghanei, Shamspour, Babaei, Abadi, Jafari, Harandi (bib0660) 2010; 188
Tahmasbpour Marzony, Ghanei, Panahi (bib0740) 2016; 42
Pohanka, Stetina, Svobodova, Ruttkay-Nedecky, Jilkova, Sochor, Sobotka, Adam, Kizek (bib0570) 2013; 36
Jin, Ray, Ray (bib0270) 2016; 3
Lagunas-Rangel (bib0340) 2019; 80
Trammell, Schmidt, Weidemann, Redpath, Jaksch, Dellinger, Li, Abel, Migaud, Brenner (bib0760) 2016; 7
Panahi, Ghanei, Bashiri, Hajihashemi, Sahebkar (bib0520) 2015; 65
Laskin, Black, Jan, Sinko, Heindel, Sunil, Heck, Laskin (bib0345) 2010; 1203
Canto, Houtkooper, Pirinen, Youn, Oosterveer, Cen, Fernandez-Marcos, Yamamoto, Andreux, Cettour-Rose, Gademann, Rinsch, Schoonjans, Sauve, Auwerx (bib0085) 2012; 15
Conze, Brenner, Kruger (bib0110) 2019; 9
Udasin, Wen, Bircsak, Aleksunes, Shakarjian, Kong, Heck, Laskin, Laskin (bib0765) 2016; 149
Gochman, Mahajna, Reznick (bib0180) 2011; 31
Darvishi, Panahi, Ghanei, Farahmand (bib0125) 2017; 120
Eisemann, Pascal (bib0145) 2019; 77
Rappeneau, Baeza-Squiban, Jeulin, Marano (bib0600) 2000; 54
Shohrati, Karimzadeh, Saburi, Khalili, Ghanei (bib0670) 2014; 26
Stenger, Popp, John, Siegert, Tsoutsoulopoulos, Schmidt, Muckter, Gudermann, Thiermann, Steinritz (bib0720) 2017; 91
Singh, Chhabra, Ndiaye, Garcia-Peterson, Mack, Ahmad (bib0680) 2018; 28
Yoshino, Baur, Imai (bib0830) 2018; 27
Tahmasbpour Marzony, Nejad-Moghadam, Ghanei, Panahi (bib0745) 2016; 45
Mol, Smith (bib0485) 1996; 100
Meng, Pei, Feng, Zhao, Chen, Shi, Xu, Lin, Sun, Xiao (bib0465) 2017; 7
Rahmani, Abdollahi (bib0590) 2017; 91
Anderson, Byers, Vesely (bib0015) 2000; 20
Yourick, Dawson, Mitcheltree (bib0850) 1995; 15
Zhou, Wang, Yang, Lin, Zhang, Zhao (bib0870) 2011; 77
Liszt, Ford, Kurtev, Guarente (bib0365) 2005; 280
Meier, Millard, Moser (bib0450) 2000; 20
Ghanei, Adibi, Farhat, Aslani (bib0175) 2008; 5
Liao, Ji, Helleday, Ying (bib0355) 2018; 19
Rothmiller, Schroder, Strobelt, Wolf, Wang, Jiang, Worek, Steinritz, Thiermann, Schmidt (bib0635) 2018; 293
Yang, Yang, Baur, Perez, Matsui, Carmona, Lamming, Souza-Pinto, Bohr, Rosenzweig, de Cabo, Sauve, Sinclair (bib0820) 2007; 130
Pino, Pietka-Ottlik, Billack (bib0550) 2014; 33
Black, Read (bib0050) 1995; 25
Jafari (bib0250) 2007; 231
Elsayed, Omaye, Klain, Korte (bib0150) 1992; 72
Steinritz, Thiermann (bib0695) 2016
Liu, Jiang, Xiao, Cheng, Mei, Zheng, Wang, Zhang, Zhou, Zhou, Zhang (bib0370) 2016; 4
Pal, Tewari-Singh, Gu, Agarwal, Huang, Day, White, Agarwal (bib0510) 2009; 47
Jozsef, Filep (bib0280) 2003; 35
Yourick, Dawson, Mitcheltree (bib0840) 1992; 117
Menacher, Steinritz, Schmidt, Popp, Worek, Gudermann, Thiermann, Balszuweit (bib0455) 2018; 293
Mol, de Vries-van de Ruit (bib0480) 1992; 6
Yourick, Dawson, Benton, Craig, Mitcheltree (bib0845) 1993; 84
Beigi Harchegani, Khor, Tahmasbpour, Ghatrehsamani, Bakhtiari Kaboutaraki, Shahriary (bib0045) 2019; 38
Kim, Park, Kim, Lee, Lee, Jeon, So, Kim, Kim (bib0310) 2011; 108
Hogan, Chini, Chini (bib0230) 2019; 10
Shohrati, Haji Hosseini, Esfandiari, Najafian, Najafian, Golbedagh (bib0665) 2014; 16
Ba, Garg (bib0030) 2011; 178
Tay, Krishnan, Sankar, Chong, Chuang, Tan, Kolinjivadi, Kappei, Ito (bib0755) 2018; 24
Tahmasbpour, Reza Emami, Ghanei, Panahi (bib0735) 2015; 27
Martens, Smith (bib0420) 2008; 27
Black, Joseph, Casillas, Heck, Gerecke, Sinko, Laskin, Laskin (bib0055) 2010; 245
Panahi, Abdolghaffari, Sahebkar (bib0535) 2018; 119
Meier (bib0435) 1996; 12
Mendes, Lelis, Santos (bib0460) 2017; 38
Chen, Jia, Song, Zhang (bib0105) 2018; 9
Petrali, Oglesby, Meier (bib0545) 1990; 14
Yang, Mohammed, Zhang, Sauve (bib0825) 2019; 294
Smith, Gross, Chan, Meier (bib0685) 1990; 6
Balszuweit, John, Schmidt, Kehe, Thiermann, Steinritz (bib0035) 2013; 206
Pohanka, Martinkova, Brtnicky, Kynicky (bib0575) 2017; 27
Wang, Wan, Ye, Qiu, Pei, Jiang, Pang, Huang, Liang, Ling, Lin, Zhang, Yang (bib0785) 2018; 17
Zhang, Riviere, Monteiro-Riviere (bib0855) 1995; 96
Guse (bib0200) 2015; 1854
Kaboudanian Ardestani, Taravati, Kianmehr, Hajizadeh Dastjerdi, Pourfarzam, Soroush, Naghizadeh, Ghazanfari (bib0285) 2018; 30
Nobakht, Oskouie, Aliannejad, Rezaei-Tavirani, Tavallaie, Baghban, Taheri, Keramati, Alamdari (bib0505) 2016; 39
Williamson, Lund, Krebs (bib0810) 1967; 103
Cowan, Yourick, Hurst, Broomfield, Smith (bib0120) 1993; 9
Sorrentino, Romani, Mouchiroud, Beck, Zhang, D’Amico, Moullan, Potenza, Schmid, Rietsch, Counts, Auwerx (bib0690) 2017; 552
Hardej, Billack (bib0215) 2007; 23
Martens (bib0415) 1996; 15
Balszuweit, Menacher, Schmidt, Kehe, Popp, Worek, Thiermann, Steinritz (bib0040) 2016; 244
Mol, de Vries, Kluivers (bib0495) 1991; 107
Fischbach, Kruger, Hampp, Assmann, Rank, Hufnagel, Stockl, Fischer, Veith, Rossatti, Ganz, Ferrando-May, Hartwig, Hauser, Wiesmuller, Burkle, Mangerich (bib0160) 2018; 46
Steinritz, Schmidt, Simons, Ibrahim, Morguet, Balszuweit, Thiermann, Kehe, Bloch, Bolck (bib0710) 2014; 219c
Zubel, Burkle, Mangerich (bib0875) 2018; 293
Kumar, Tewari-Singh, Agarwal, Jain, Inturi, Kant, White, Agarwal (bib0335) 2015; 235
Ludlum, Austin-Ritchie, Hagopian, Niu, Yu (bib0385) 1994; 91
Anderson, Taylor, Fetterer, Holmes (bib0020) 2009; 263
Lin, Bernstein, Vaughan (bib0360) 1994; 42
Garrido, Djouder (bib0165) 2017; 3
Kilic, Ortatatli, Sezigen, Eyison, Kenar (bib0305) 2018; 37
Pohanka, Sobotka, Jilkova, Stetina (bib0565) 2011; 34
Taravati, Ardestani, Soroush, Faghihzadeh, Ghazanfari, Jalilvand, Naghizadeh, Fallahi (bib0750) 2012; 34
Meier, Gross, Papirmeister (bib0445) 1987; 39
Min, Gao, Yu (bib0470) 2018; 9
Detheux, Jijakli, Lison (bib0135) 1997; 71
Palmeira, Teodoro, Amorim, Steegborn, Sinclair, Rolo (bib0515) 2019; 141
Braidy, Berg, Clement, Khorshidi, Poljak, Jayasena, Grant, Sachdev (bib0075) 2019; 30
Pita, Marco-Contelles, Ramos, Pino, Romero (bib0555) 2014; 88
Steinritz, Elischer, Balszuweit, Gonder, Heinrich, Bloch, Thiermann, Kehe (bib0705) 2009; 188
Rebholz, Kehe, Ruzicka, Rupec (bib0615) 2008; 128
Layali, Shahriary, Rahmani Talatappe, Tahmasbpour, Rostami, Beigi Harchegani (bib0350) 2018; 40
Sawyer, Hamilton (bib0645) 2000; 14
Matasic, Brenner, London (bib0425) 2018; 314
Rosenthal, Simbulan-Rosenthal, Liu, Velena, Anderson, Benton, Wang, Smith, Ray, Smulson (bib0630) 2001; 117
Ray Chaudhuri, Nussenzweig (bib0610) 2017; 18
Kehe, Balszuweit, Steinritz, Thiermann (bib0300) 2009; 263
Steinritz, Emmler, Hintz, Worek, Kreppel, Szinicz, Kehe (bib0700) 2007; 80
Joseph, Composto, Perez, Kim, Casillas, Heindel, Young, Lacey, Saxena, Guillon, Croutch, Laskin, Heck (bib0275) 2018; 293
Mangerich, Esser (bib0405) 2014; 88
Vijayaraghavan, Kulkarni, Pant, Kumar, Rao, Gupta, Gautam, Ganesan (bib0770) 2005; 202
Mangerich, Burkle (bib0400) 2012; 2012
Blaha, Bowers, Kohl, DuBose, Walker (bib0060) 2000; 13
Debiak, Kehe, Burkle (bib0130) 2009; 263
Shakarjian, Bhatt, Gordon, Chang, Casbohm, Rudge, Kiser, Sabourin, Casillas, Ohman-Strickland, Riley, Gerecke (bib0650) 2006; 26
Preiss, Handler (bib0580) 1958; 233
Hou, Lautrup, Cordonnier, Wang, Croteau, Zavala, Zhang, Moritoh, O’Connell, Baptiste, Stevnsner, Mattson, Bohr (bib0235) 2018; 115
Cowan, Broomfield, Smith (bib0115) 1992; 8
Ham, Hong, Lee, Kwon, Kim, Song (bib0205) 2012; 258
Wei, Graeff, Yue (bib0790) 2014; 5
Yourick, Clark, Mitcheltree (bib0835) 1991; 17
Love, Pollak, Dolle, Niere, Chen, Oliveri, Amaya, Patel, Ziegler (bib0375) 2015; 112
Luo, Kraus (bib0390) 2012; 26
Hinshaw, Lodhi, Hurley, Atkins, Dabrowska (bib0225) 1999; 156
Xiao, Wang, Handy, Loscalzo (bib0815) 2018; 28
Zhang, Chen, Pei, Gao, Shi, Sun, Xu, Zhao, Meng, Xiao (bib0865) 2019; 367
Weinberger, Malaviya, Sunil, Venosa, Heck, Laskin, Laskin (bib0805) 2016; 305
Aredia, Scovassi (bib0025) 2014; 92
Borna, Hosseini Qale Noe, Harchegani, Talatappe, Ghatrehsamani, Ghanei, Shahriary (bib0070) 2019; 31
Steinritz, Striepling, Rudolf, Schroder-Kraft, Puschel, Hullard-Pulstinger, Koller, Thiermann, Gandor, Gawlik, John (bib0715) 2016; 244
Abel, Bubel, Simper, Powell, McClellan, Andreeff, MacLeod, DiGiovanni (bib0005) 2011; 255
Kirkland (bib0315) 2012; 733
Fingleton (bib0155) 2017; 1864
Dillman, McGary, Schlager (bib0140) 2004; 18
Burkle, Virag (bib0080) 2013; 34
Rosenthal, Simbulan-Rosenthal, Iyer, Spoonde, Smith
Liu (10.1016/j.toxlet.2020.01.024_bib0370) 2016; 4
Korkmaz (10.1016/j.toxlet.2020.01.024_bib0320) 2008; 29
Ray Chaudhuri (10.1016/j.toxlet.2020.01.024_bib0610) 2017; 18
Kehe (10.1016/j.toxlet.2020.01.024_bib0295) 2008; 82
Preiss (10.1016/j.toxlet.2020.01.024_bib0580) 1958; 233
Trammell (10.1016/j.toxlet.2020.01.024_bib0760) 2016; 7
Meier (10.1016/j.toxlet.2020.01.024_bib0435) 1996; 12
Steinritz (10.1016/j.toxlet.2020.01.024_bib0705) 2009; 188
Yourick (10.1016/j.toxlet.2020.01.024_bib0845) 1993; 84
Black (10.1016/j.toxlet.2020.01.024_bib0055) 2010; 245
Palmeira (10.1016/j.toxlet.2020.01.024_bib0515) 2019; 141
Chen (10.1016/j.toxlet.2020.01.024_bib0105) 2018; 9
Hou (10.1016/j.toxlet.2020.01.024_bib0235) 2018; 115
Stromland (10.1016/j.toxlet.2020.01.024_bib0725) 2019; 47
Gochman (10.1016/j.toxlet.2020.01.024_bib0180) 2011; 31
Steinritz (10.1016/j.toxlet.2020.01.024_bib0700) 2007; 80
Blaha (10.1016/j.toxlet.2020.01.024_bib0060) 2000; 13
Taravati (10.1016/j.toxlet.2020.01.024_bib0750) 2012; 34
Meier (10.1016/j.toxlet.2020.01.024_bib0440) 1992; 113
Kumar (10.1016/j.toxlet.2020.01.024_bib0335) 2015; 235
Chaitanya (10.1016/j.toxlet.2020.01.024_bib0100) 2010; 8
Mishra (10.1016/j.toxlet.2020.01.024_bib0475) 2017; 1863
Mol (10.1016/j.toxlet.2020.01.024_bib0485) 1996; 100
Shohrati (10.1016/j.toxlet.2020.01.024_bib0660) 2010; 188
Wagner (10.1016/j.toxlet.2020.01.024_bib0780) 2019; 312
Ba (10.1016/j.toxlet.2020.01.024_bib0030) 2011; 178
Pohanka (10.1016/j.toxlet.2020.01.024_bib0575) 2017; 27
Shakarjian (10.1016/j.toxlet.2020.01.024_bib0650) 2006; 26
Udasin (10.1016/j.toxlet.2020.01.024_bib0765) 2016; 149
Lin (10.1016/j.toxlet.2020.01.024_bib0360) 1994; 42
Ghanei (10.1016/j.toxlet.2020.01.024_bib0170) 2010; 11
Gross (10.1016/j.toxlet.2020.01.024_bib0195) 1985; 81
Yoshino (10.1016/j.toxlet.2020.01.024_bib0830) 2018; 27
Yang (10.1016/j.toxlet.2020.01.024_bib0825) 2019; 294
Zhou (10.1016/j.toxlet.2020.01.024_bib0870) 2011; 77
Canto (10.1016/j.toxlet.2020.01.024_bib0095) 2015; 22
Mol (10.1016/j.toxlet.2020.01.024_bib0480) 1992; 6
Tahmasbpour Marzony (10.1016/j.toxlet.2020.01.024_bib0740) 2016; 42
Zhang (10.1016/j.toxlet.2020.01.024_bib0865) 2019; 367
Laskin (10.1016/j.toxlet.2020.01.024_bib0345) 2010; 1203
Sun (10.1016/j.toxlet.2020.01.024_bib0730) 2018; 286
Meier (10.1016/j.toxlet.2020.01.024_bib0450) 2000; 20
Liao (10.1016/j.toxlet.2020.01.024_bib0355) 2018; 19
Balszuweit (10.1016/j.toxlet.2020.01.024_bib0035) 2013; 206
Williamson (10.1016/j.toxlet.2020.01.024_bib0810) 1967; 103
Anderson (10.1016/j.toxlet.2020.01.024_bib0015) 2000; 20
Zhang (10.1016/j.toxlet.2020.01.024_bib0855) 1995; 96
Aredia (10.1016/j.toxlet.2020.01.024_bib0025) 2014; 92
Abel (10.1016/j.toxlet.2020.01.024_bib0005) 2011; 255
Borna (10.1016/j.toxlet.2020.01.024_bib0070) 2019; 31
Meng (10.1016/j.toxlet.2020.01.024_bib0465) 2017; 7
Debiak (10.1016/j.toxlet.2020.01.024_bib0130) 2009; 263
Dillman (10.1016/j.toxlet.2020.01.024_bib0140) 2004; 18
Steinritz (10.1016/j.toxlet.2020.01.024_bib0715) 2016; 244
Jiang (10.1016/j.toxlet.2020.01.024_bib0265) 2019; 225
Mendes (10.1016/j.toxlet.2020.01.024_bib0460) 2017; 38
Jin (10.1016/j.toxlet.2020.01.024_bib0270) 2016; 3
Min (10.1016/j.toxlet.2020.01.024_bib0470) 2018; 9
Canto (10.1016/j.toxlet.2020.01.024_bib0085) 2012; 15
Shohrati (10.1016/j.toxlet.2020.01.024_bib0665) 2014; 16
Tay (10.1016/j.toxlet.2020.01.024_bib0755) 2018; 24
Kaboudanian Ardestani (10.1016/j.toxlet.2020.01.024_bib0285) 2018; 30
Kirkland (10.1016/j.toxlet.2020.01.024_bib0315) 2012; 733
Mol (10.1016/j.toxlet.2020.01.024_bib0490) 1989; 98
Conze (10.1016/j.toxlet.2020.01.024_bib0110) 2019; 9
Kilic (10.1016/j.toxlet.2020.01.024_bib0305) 2018; 37
Virág (10.1016/j.toxlet.2020.01.024_bib0775) 2006
Gould (10.1016/j.toxlet.2020.01.024_bib0185) 2009; 328
Darvishi (10.1016/j.toxlet.2020.01.024_bib0125) 2017; 120
Yourick (10.1016/j.toxlet.2020.01.024_bib0840) 1992; 117
Martens (10.1016/j.toxlet.2020.01.024_bib0415) 1996; 15
Rahmani (10.1016/j.toxlet.2020.01.024_bib0590) 2017; 91
Balszuweit (10.1016/j.toxlet.2020.01.024_bib0040) 2016; 244
Shohrati (10.1016/j.toxlet.2020.01.024_bib0670) 2014; 26
Neidle (10.1016/j.toxlet.2020.01.024_bib0500) 2005; 5
Steinritz (10.1016/j.toxlet.2020.01.024_bib0695) 2016
Ludlum (10.1016/j.toxlet.2020.01.024_bib0385) 1994; 91
Hamity (10.1016/j.toxlet.2020.01.024_bib0210) 2017; 158
Lagunas-Rangel (10.1016/j.toxlet.2020.01.024_bib0340) 2019; 80
Shi (10.1016/j.toxlet.2020.01.024_bib0655) 2013; 4
Detheux (10.1016/j.toxlet.2020.01.024_bib0135) 1997; 71
Tahmasbpour Marzony (10.1016/j.toxlet.2020.01.024_bib0745) 2016; 45
Weidele (10.1016/j.toxlet.2020.01.024_bib0800) 2017; 52
Liszt (10.1016/j.toxlet.2020.01.024_bib0365) 2005; 280
Jain (10.1016/j.toxlet.2020.01.024_bib0260) 2015; 285
Mangerich (10.1016/j.toxlet.2020.01.024_bib0405) 2014; 88
Steinritz (10.1016/j.toxlet.2020.01.024_bib0710) 2014; 219c
Zubel (10.1016/j.toxlet.2020.01.024_bib0880) 2019; 93
Yourick (10.1016/j.toxlet.2020.01.024_bib0850) 1995; 15
Black (10.1016/j.toxlet.2020.01.024_bib0050) 1995; 25
Rosenthal (10.1016/j.toxlet.2020.01.024_bib0630) 2001; 117
Kauppinen (10.1016/j.toxlet.2020.01.024_bib0290) 2013; 25
Aguilar-Quesada (10.1016/j.toxlet.2020.01.024_bib0010) 2007; 14
Jozsef (10.1016/j.toxlet.2020.01.024_bib0280) 2003; 35
Zhang (10.1016/j.toxlet.2020.01.024_bib0860) 2017; 55
Mangerich (10.1016/j.toxlet.2020.01.024_bib0410) 2016; 244
Wang (10.1016/j.toxlet.2020.01.024_bib0785) 2018; 17
Pal (10.1016/j.toxlet.2020.01.024_bib0510) 2009; 47
Rosenthal (10.1016/j.toxlet.2020.01.024_bib0625) 1998; 111
Kehe (10.1016/j.toxlet.2020.01.024_bib0300) 2009; 263
Elsayed (10.1016/j.toxlet.2020.01.024_bib0150) 1992; 72
Pita (10.1016/j.toxlet.2020.01.024_bib0555) 2014; 88
Sawyer (10.1016/j.toxlet.2020.01.024_bib0645) 2000; 14
Weinberger (10.1016/j.toxlet.2020.01.024_bib0805) 2016; 305
Guse (10.1016/j.toxlet.2020.01.024_bib0200) 2015; 1854
Love (10.1016/j.toxlet.2020.01.024_bib0375) 2015; 112
Ludlum (10.1016/j.toxlet.2020.01.024_bib0380) 1986; 38
Braidy (10.1016/j.toxlet.2020.01.024_bib0075) 2019; 30
Panahi (10.1016/j.toxlet.2020.01.024_bib0525) 2016; 13
Pino (10.1016/j.toxlet.2020.01.024_bib0550) 2014; 33
Ghanei (10.1016/j.toxlet.2020.01.024_bib0175) 2008; 5
Kim (10.1016/j.toxlet.2020.01.024_bib0310) 2011; 108
Singh (10.1016/j.toxlet.2020.01.024_bib0680) 2018; 28
Cowan (10.1016/j.toxlet.2020.01.024_bib0115) 1992; 8
Jafari (10.1016/j.toxlet.2020.01.024_bib0255) 2010; 48
Menacher (10.1016/j.toxlet.2020.01.024_bib0455) 2018; 293
Petrali (10.1016/j.toxlet.2020.01.024_bib0545) 1990; 14
Fingleton (10.1016/j.toxlet.2020.01.024_bib0155) 2017; 1864
Panahi (10.1016/j.toxlet.2020.01.024_bib0520) 2015; 65
Meier (10.1016/j.toxlet.2020.01.024_bib0445) 1987; 39
Cowan (10.1016/j.toxlet.2020.01.024_bib0120) 1993; 9
Tahmasbpour (10.1016/j.toxlet.2020.01.024_bib0735) 2015; 27
Ries (10.1016/j.toxlet.2020.01.024_bib0620) 2009; 263
Beigi Harchegani (10.1016/j.toxlet.2020.01.024_bib0045) 2019; 38
Hardej (10.1016/j.toxlet.2020.01.024_bib0215) 2007; 23
Mangerich (10.1016/j.toxlet.2020.01.024_bib0400) 2012; 2012
Kumar (10.1016/j.toxlet.2020.01.024_bib0330) 2001; 134
Panahi (10.1016/j.toxlet.2020.01.024_bib0535) 2018; 119
Plahovinsak (10.1016/j.toxlet.2020.01.024_bib0560) 2016; 35
Weidele (10.1016/j.toxlet.2020.01.024_bib0795) 2010; 80
Mol (10.1016/j.toxlet.2020.01.024_bib0495) 1991; 107
Rothmiller (10.1016/j.toxlet.2020.01.024_bib0635) 2018; 293
Jacobson (10.1016/j.toxlet.2020.01.024_bib0245) 2018; 1813
Sorrentino (10.1016/j.toxlet.2020.01.024_bib0690) 2017; 552
Bogan (10.1016/j.toxlet.2020.01.024_bib0065) 2008; 28
Burkle (10.1016/j.toxlet.2020.01.024_bib0080) 2013; 34
Anderson (10.1016/j.toxlet.2020.01.024_bib0020) 2009; 263
Garrido (10.1016/j.toxlet.2020.01.024_bib0165) 2017; 3
Ham (10.1016/j.toxlet.2020.01.024_bib0205) 2012; 258
Smith (10.1016/j.toxlet.2020.01.024_bib0685) 1990; 6
Panahi (10.1016/j.toxlet.2020.01.024_bib0530) 2017; 118
Fischbach (10.1016/j.toxlet.2020.01.024_bib0160) 2018; 46
Nobakht (10.1016/j.toxlet.2020.01.024_bib0505) 2016; 39
Rappeneau (10.1016/j.toxlet.2020.01.024_bib0605) 2000; 58
Simbulan-Rosenthal (10.1016/j.toxlet.2020.01.024_bib0675) 2006; 227
Hogan (10.1016/j.toxlet.2020.01.024_bib0230) 2019; 10
Purohit (10.1016/j.toxlet.2020.01.024_bib0585) 2019; 11
Graham (10.1016/j.toxlet.2020.01.024_bib0190) 2005; 4
Luo (10.1016/j.toxlet.2020.01.024_bib0390) 2012; 26
Rebholz (10.1016/j.toxlet.2020.01.024_bib0615) 2008; 128
Joseph (10.1016/j.toxlet.2020.01.024_bib0275) 2018; 293
Matasic (10.1016/j.toxlet.2020.01.024_bib0425) 2018; 314
Mei (10.1016/j.toxlet.2020.01.024_bib0430) 2014; 1
Layali (10.1016/j.toxlet.2020.01.024_bib0350) 2018; 40
Papirmeister (10.1016/j.toxlet.2020.01.024_bib0540) 1985; 5
Yang (10.1016/j.toxlet.2020.01.024_bib0820) 2007; 130
Malaviya (10.1016/j.toxlet.2020.01.024_bib0395) 2010; 248
Vijayaraghavan (10.1016/j.toxlet.2020.01.024_bib0770) 2005; 202
Hinshaw (10.1016/j.toxlet.2020.01.024_bib0225) 1999; 156
Pohanka (10.1016/j.toxlet.2020.01.024_bib0565) 2011; 34
Yourick (10.1016/j.toxlet.2020.01.024_bib0835) 1991; 17
Rappeneau (10.1016/j.toxlet.2020.01.024_bib0600) 2000; 54
Xiao (10.1016/j.toxlet.2020.01.024_bib0815) 2018; 28
Jafari (10.1016/j.toxlet.2020.01.024_bib0250) 2007; 231
Martens (10.1016/j.toxlet.2020.01.024_bib0420) 2008; 27
Stenger (10.1016/j.toxlet.2020.01.024_bib0720) 2017; 91
Salminen (10.1016/j.toxlet.2020.01.024_bib0640) 2013; 14
Pohanka (10.1016/j.toxlet.2020.01.024_bib0570) 2013; 36
Rajman (10.1016/j.toxlet.2020.01.024_bib0595) 2018; 27
Eisemann (10.1016/j.toxlet.2020.01.024_bib0145) 2019; 77
Hassa (10.1016/j.toxlet.2020.01.024_bib0220) 2006
Hwang (10.1016/j.toxlet.2020.01.024_bib0240) 2017; 74
Zubel (10.1016/j.toxlet.2020.01.024_bib0875) 2018; 293
Kulkarni (10.1016/j.toxlet.2020.01.024_bib0325) 2014; 20
Canto (10.1016/j.toxlet.2020.01.024_bib0090) 2013; 34
Wei (10.1016/j.toxlet.2020.01.024_bib0790) 2014; 5
References_xml – volume: 227
  start-page: 21
  year: 2006
  end-page: 35
  ident: bib0675
  article-title: Calmodulin mediates sulfur mustard toxicity in human keratinocytes
  publication-title: Toxicology
– volume: 117
  start-page: 104
  year: 1992
  end-page: 109
  ident: bib0840
  article-title: Sulfur mustard-induced microvesication in hairless guinea pigs: effect of short-term niacinamide administration
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 8
  start-page: 129
  year: 1992
  end-page: 138
  ident: bib0115
  article-title: Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-L-cysteine or dexamethasone
  publication-title: Cell Biol. Toxicol.
– volume: 286
  start-page: 111
  year: 2018
  end-page: 118
  ident: bib0730
  article-title: Advanced biotherapy for the treatment of sulfur mustard poisoning
  publication-title: Chem. Biol. Interact.
– volume: 1
  start-page: 28
  year: 2014
  ident: bib0430
  article-title: The injury progression of T lymphocytes in a mouse model with subcutaneous injection of a high dose of sulfur mustard
  publication-title: Mil. Med. Res.
– volume: 255
  start-page: 176
  year: 2011
  end-page: 183
  ident: bib0005
  article-title: Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 16
  year: 2014
  ident: bib0665
  article-title: Serum matrix metalloproteinase levels in patients exposed to sulfur mustard
  publication-title: Iran. Red Crescent Med. J.
– volume: 6
  start-page: 285
  year: 1990
  end-page: 291
  ident: bib0685
  article-title: The use of human epidermal keratinocytes in culture as a model for studying the biochemical mechanisms of sulfur mustard toxicity
  publication-title: Cell Biol. Toxicol.
– volume: 202
  start-page: 180
  year: 2005
  end-page: 188
  ident: bib0770
  article-title: Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous, and oral routes
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 293
  start-page: 91
  year: 2018
  end-page: 97
  ident: bib0455
  article-title: Effects of anti-inflammatory compounds on sulfur mustard injured cells: recommendations and caveats suggested by in vitro cell culture models
  publication-title: Toxicol. Lett.
– volume: 141
  start-page: 483
  year: 2019
  end-page: 491
  ident: bib0515
  article-title: Mitohormesis and metabolic health: the interplay between ROS, cAMP and sirtuins
  publication-title: Free Radic. Biol. Med.
– volume: 107
  start-page: 439
  year: 1991
  end-page: 449
  ident: bib0495
  article-title: Effects of nicotinamide on biochemical changes and microblistering induced by sulfur mustard in human skin organ cultures
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 74
  start-page: 3347
  year: 2017
  end-page: 3362
  ident: bib0240
  article-title: Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells
  publication-title: Cell. Mol. Life Sci.: CMLS
– volume: 98
  start-page: 159
  year: 1989
  end-page: 165
  ident: bib0490
  article-title: NAD+ levels and glucose uptake of cultured human epidermal cells exposed to sulfur mustard
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 235
  start-page: 161
  year: 2015
  end-page: 171
  ident: bib0335
  article-title: Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators
  publication-title: Toxicol. Lett.
– volume: 27
  start-page: 659
  year: 2015
  end-page: 672
  ident: bib0735
  article-title: Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection
  publication-title: Inhal. Toxicol.
– volume: 91
  start-page: 2179
  year: 2017
  end-page: 2189
  ident: bib0720
  article-title: N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx
  publication-title: Arch. Toxicol.
– volume: 71
  start-page: 243
  year: 1997
  end-page: 249
  ident: bib0135
  article-title: Effect of sulphur mustard on the expression of urokinase in cultured 3T3 fibroblasts
  publication-title: Arch. Toxicol.
– volume: 25
  start-page: 1939
  year: 2013
  end-page: 1948
  ident: bib0290
  article-title: Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders
  publication-title: Cell. Signal.
– volume: 34
  start-page: 706
  year: 2012
  end-page: 713
  ident: bib0750
  article-title: Serum albumin and paraoxonase activity in Iranian veterans 20 years after sulfur mustard exposure
  publication-title: Immunopharmacol. Immunotoxicol.
– volume: 84
  start-page: 185
  year: 1993
  end-page: 197
  ident: bib0845
  article-title: Pathogenesis of 2,2’-dichlorodiethyl sulfide in hairless guinea pigs
  publication-title: Toxicology
– volume: 2012
  year: 2012
  ident: bib0400
  article-title: Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation
  publication-title: Oxid. Med. Cell. Longev.
– volume: 112
  start-page: 1386
  year: 2015
  end-page: 1391
  ident: bib0375
  article-title: NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 72
  start-page: 153
  year: 1992
  end-page: 165
  ident: bib0150
  article-title: Free radical-mediated lung response to the monofunctional sulfur mustard butyl 2-chloroethyl sulfide after subcutaneous injection
  publication-title: Toxicology
– volume: 231
  start-page: 30
  year: 2007
  end-page: 39
  ident: bib0250
  article-title: Dose- and time-dependent effects of sulfur mustard on antioxidant system in liver and brain of rat
  publication-title: Toxicology
– volume: 24
  start-page: 1747
  year: 2018
  end-page: 1755
  ident: bib0755
  article-title: RUNX poly(ADP-ribosyl)ation and BLM interaction facilitate the fanconi anemia pathway of DNA repair
  publication-title: Cell Rep.
– volume: 293
  start-page: 21
  year: 2018
  end-page: 30
  ident: bib0875
  article-title: Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: are DNA adducts suitable biomarkers of exposure?
  publication-title: Toxicol. Lett.
– volume: 25
  start-page: 167
  year: 1995
  end-page: 173
  ident: bib0050
  article-title: Biological fate of sulphur mustard, 1,1’-thiobis(2-chloroethane): identification of beta-lyase metabolites and hydrolysis products in human urine
  publication-title: Xenobiotica
– volume: 96
  start-page: 249
  year: 1995
  end-page: 262
  ident: bib0855
  article-title: Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin
  publication-title: Chem. Biol. Interact.
– volume: 206
  start-page: 496
  year: 2013
  end-page: 504
  ident: bib0035
  article-title: Silibinin as a potential therapeutic for sulfur mustard injuries
  publication-title: Chem. Biol. Interact.
– volume: 13
  start-page: 99
  year: 2000
  end-page: 111
  ident: bib0060
  article-title: Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists
  publication-title: In Vitro Mol. Toxicol.
– volume: 7
  start-page: 9433
  year: 2017
  ident: bib0465
  article-title: Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation
  publication-title: Sci. Rep.
– volume: 80
  start-page: 1103
  year: 2010
  end-page: 1112
  ident: bib0795
  article-title: Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells
  publication-title: Biochem. Pharmacol.
– volume: 733
  start-page: 14
  year: 2012
  end-page: 20
  ident: bib0315
  article-title: Niacin requirements for genomic stability
  publication-title: Mutat. Res.
– volume: 111
  start-page: 64
  year: 1998
  end-page: 71
  ident: bib0625
  article-title: Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway
  publication-title: J. Invest. Dermatol.
– start-page: 141
  year: 2006
  end-page: 152
  ident: bib0775
  article-title: PARP-1 and the Shape of Cell Death. Poly(ADP-Ribosyl)ation
– volume: 100
  start-page: 85
  year: 1996
  end-page: 93
  ident: bib0485
  article-title: Ca2+ homeostasis and Ca2+ signalling in sulphur mustard-exposed normal human epidermal keratinocytes
  publication-title: Chem. Biol. Interact.
– volume: 19
  year: 2018
  ident: bib0355
  article-title: Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments
  publication-title: EMBO Rep.
– volume: 39
  start-page: 362
  year: 2016
  end-page: 366
  ident: bib0505
  article-title: Pro-oxidant-antioxidant balance in Iranian veterans with sulfur mustard toxicity and different levels of pulmonary disorders
  publication-title: Drug Chem. Toxicol.
– volume: 14
  start-page: 3834
  year: 2013
  end-page: 3859
  ident: bib0640
  article-title: Crosstalk between oxidative stress and SIRT1: impact on the aging process
  publication-title: Int. J. Mol. Sci.
– volume: 31
  start-page: 3
  year: 2019
  end-page: 11
  ident: bib0070
  article-title: A review on proteomics analysis to reveal biological pathways and predictive proteins in sulfur mustard exposed patients: roles of inflammation and oxidative stress
  publication-title: Inhal. Toxicol.
– volume: 13
  start-page: 93
  year: 2016
  end-page: 105
  ident: bib0525
  article-title: Effects of curcuminoids-piperine combination on systemic oxidative stress, clinical symptoms and quality of life in subjects with chronic pulmonary complications due to sulfur mustard: a randomized controlled trial
  publication-title: J. Diet. Suppl.
– volume: 17
  start-page: 89
  year: 2018
  end-page: 98
  ident: bib0785
  article-title: Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1alpha/mitochondrial biosynthesis pathway
  publication-title: Redox Biol.
– volume: 33
  start-page: 32
  year: 2014
  end-page: 41
  ident: bib0550
  article-title: Selected ebselen analogs reduce mechlorethamine toxicity in vitro
  publication-title: Cutan. Ocul. Toxicol.
– volume: 36
  start-page: 270
  year: 2013
  end-page: 276
  ident: bib0570
  article-title: Sulfur mustard causes oxidative stress and depletion of antioxidants in muscles, livers, and kidneys of Wistar rats
  publication-title: Drug Chem. Toxicol.
– volume: 26
  start-page: 239
  year: 2006
  end-page: 246
  ident: bib0650
  article-title: Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure
  publication-title: J. Appl. Toxicol.: JAT
– volume: 15
  start-page: 838
  year: 2012
  end-page: 847
  ident: bib0085
  article-title: The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
  publication-title: Cell Metab.
– volume: 88
  start-page: 1909
  year: 2014
  end-page: 1911
  ident: bib0405
  article-title: Chemical warfare in the First World War: reflections 100 years later
  publication-title: Arch. Toxicol.
– volume: 120
  start-page: 120
  year: 2017
  end-page: 130
  ident: bib0125
  article-title: Investigating prevalence and pattern of long-term cardiovascular disorders in sulphur mustard-exposed victims and determining proper biomarkers for early defining, monitoring and analysis of patients’ feedback on therapy
  publication-title: Basic Clin. Pharmacol. Toxicol.
– volume: 314
  start-page: H839
  year: 2018
  end-page: H852
  ident: bib0425
  article-title: Emerging potential benefits of modulating NAD(+) metabolism in cardiovascular disease
  publication-title: Am. J. Physiol. Heart Circ. Physiol.
– volume: 156
  start-page: 17
  year: 1999
  end-page: 29
  ident: bib0225
  article-title: Activation of poly [ADP-Ribose] polymerase in endothelial cells and keratinocytes: role in an in vitro model of sulfur mustard-mediated vesication
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 244
  start-page: 56
  year: 2016
  end-page: 71
  ident: bib0410
  article-title: Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences
  publication-title: Toxicol. Lett.
– volume: 9
  start-page: 1453
  year: 2018
  ident: bib0105
  article-title: Therapeutic potential of nitrogen mustard based hybrid molecules
  publication-title: Front. Pharmacol.
– volume: 245
  start-page: 352
  year: 2010
  end-page: 360
  ident: bib0055
  article-title: Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 28
  start-page: 643
  year: 2018
  end-page: 661
  ident: bib0680
  article-title: The role of sirtuins in antioxidant and redox signaling
  publication-title: Antioxid. Redox Signal.
– volume: 37
  start-page: 332
  year: 2018
  end-page: 337
  ident: bib0305
  article-title: Acute intensive care unit management of mustard gas victims: the Turkish experience
  publication-title: Cutan. Ocul. Toxicol.
– volume: 293
  start-page: 77
  year: 2018
  end-page: 81
  ident: bib0275
  article-title: Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug
  publication-title: Toxicol. Lett.
– volume: 14
  start-page: 253
  year: 1990
  end-page: 262
  ident: bib0545
  article-title: Ultrastructural correlates of the protection afforded by niacinamide against sulfur mustard-induced cytotoxicity of human lymphocytes in vitro
  publication-title: Ultrastruct. Pathol.
– volume: 30
  start-page: 483
  year: 2018
  end-page: 491
  ident: bib0285
  article-title: Altered levels of GST activity, Vit C, TPX and Cu in individuals with long-term sulfur mustard-induced lung complications
  publication-title: Inhal. Toxicol.
– volume: 27
  start-page: 529
  year: 2018
  end-page: 547
  ident: bib0595
  article-title: Therapeutic potential of NAD-boosting molecules: the in vivo evidence
  publication-title: Cell Metab.
– volume: 118
  start-page: 3549
  year: 2017
  end-page: 3560
  ident: bib0530
  article-title: Ocular effects of sulfur mustard and therapeutic approaches
  publication-title: J. Cell. Biochem.
– volume: 293
  start-page: 51
  year: 2018
  end-page: 61
  ident: bib0635
  article-title: Sulfur mustard resistant keratinocytes obtained elevated glutathione levels and other changes in the antioxidative defense mechanism
  publication-title: Toxicol. Lett.
– volume: 35
  start-page: 208
  year: 2016
  end-page: 217
  ident: bib0560
  article-title: Selection of non-steroidal anti-inflammatory drug and treatment regimen for sulfur mustard-induced cutaneous lesions
  publication-title: Cutan. Ocul. Toxicol.
– volume: 23
  start-page: 209
  year: 2007
  end-page: 221
  ident: bib0215
  article-title: Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity
  publication-title: Toxicol. Ind. Health
– volume: 20
  start-page: S129
  year: 2000
  end-page: 132
  ident: bib0015
  article-title: Treatment of sulfur mustard (HD)-induced lung injury
  publication-title: J. Appl. Toxicol.: JAT
– volume: 178
  start-page: 946
  year: 2011
  end-page: 955
  ident: bib0030
  article-title: Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases
  publication-title: Am. J. Pathol.
– volume: 11
  year: 2019
  ident: bib0585
  article-title: Metabolic regulation of redox balance in cancer
  publication-title: Cancers
– volume: 55
  start-page: 68
  year: 2017
  end-page: 73
  ident: bib0860
  article-title: Early oxidative stress, DNA damage and inflammation resulting from subcutaneous injection of sulfur mustard into mice
  publication-title: Environ. Toxicol. Pharmacol.
– volume: 80
  start-page: 2199
  year: 2007
  end-page: 2201
  ident: bib0700
  article-title: Apoptosis in sulfur mustard treated A549 cell cultures
  publication-title: Life Sci.
– volume: 65
  start-page: 567
  year: 2015
  end-page: 573
  ident: bib0520
  article-title: Short-term curcuminoid supplementation for chronic pulmonary complications due to sulfur mustard intoxication: positive results of a randomized double-blind placebo-controlled trial
  publication-title: Drug Res.
– volume: 34
  start-page: 85
  year: 2011
  end-page: 91
  ident: bib0565
  article-title: Oxidative stress after sulfur mustard intoxication and its reduction by melatonin: efficacy of antioxidant therapy during serious intoxication
  publication-title: Drug Chem. Toxicol.
– volume: 5
  start-page: S134
  year: 1985
  end-page: 149
  ident: bib0540
  article-title: Molecular basis for mustard-induced vesication
  publication-title: Fundam. Appl. Toxicol.
– volume: 3
  start-page: 393
  year: 2016
  end-page: 400
  ident: bib0270
  article-title: Sulfur mustard-stimulated proteases and their inhibitors in a cultured normal human epidermal keratinocytes model: a potential approach for anti-vesicant drug development
  publication-title: Toxicol. Rep.
– volume: 225
  start-page: 20
  year: 2019
  end-page: 28
  ident: bib0265
  article-title: Nicotinamide riboside protects against liver fibrosis induced by CCl4 via regulating the acetylation of Smads signaling pathway
  publication-title: Life Sci.
– volume: 263
  start-page: 26
  year: 2009
  end-page: 31
  ident: bib0620
  article-title: Matrix metalloproteinase-9 expression and release from skin fibroblasts interacting with keratinocytes: upregulation in response to sulphur mustard
  publication-title: Toxicology
– volume: 52
  start-page: 12
  year: 2017
  end-page: 23
  ident: bib0800
  article-title: The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
  publication-title: DNA Rep.
– volume: 27
  start-page: 513
  year: 2018
  end-page: 528
  ident: bib0830
  article-title: NAD(+) intermediates: the biology and therapeutic potential of NMN and NR
  publication-title: Cell Metab.
– volume: 134
  start-page: 1
  year: 2001
  end-page: 12
  ident: bib0330
  article-title: Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes
  publication-title: Chem. Biol. Interact.
– volume: 27
  start-page: 408
  year: 2017
  end-page: 416
  ident: bib0575
  article-title: Changes in the oxidative stress/anti-oxidant system after exposure to sulfur mustard and antioxidant strategies in the therapy, a review
  publication-title: Toxicol. Mech. Methods
– volume: 5
  start-page: 95
  year: 2008
  end-page: 100
  ident: bib0175
  article-title: Late respiratory effects of sulfur mustard: how is the early symptoms severity involved?
  publication-title: Chron. Respir. Dis.
– volume: 233
  start-page: 488
  year: 1958
  end-page: 492
  ident: bib0580
  article-title: Biosynthesis of diphosphopyridine nucleotide. I. Identification of intermediates
  publication-title: J. Biol. Chem.
– volume: 244
  start-page: 112
  year: 2016
  end-page: 120
  ident: bib0715
  article-title: Medical documentation, bioanalytical evidence of an accidental human exposure to sulfur mustard and general therapy recommendations
  publication-title: Toxicol. Lett.
– volume: 42
  start-page: 217
  year: 2016
  end-page: 226
  ident: bib0740
  article-title: Oxidative stress and altered expression of peroxiredoxin genes family (PRDXS) and sulfiredoxin-1 (SRXN1) in human lung tissue following exposure to sulfur mustard
  publication-title: Exp. Lung Res.
– volume: 48
  start-page: 184
  year: 2010
  end-page: 192
  ident: bib0255
  article-title: Evaluation of plasma, erythrocytes, and bronchoalveolar lavage fluid antioxidant defense system in sulfur mustard-injured patients
  publication-title: Clin. Toxicol. (Phila. Pa)
– volume: 115
  start-page: E1876
  year: 2018
  end-page: E1885
  ident: bib0235
  article-title: NAD(+) supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 367
  start-page: 1
  year: 2019
  end-page: 11
  ident: bib0865
  article-title: Protective effects of polydatin against sulfur mustard-induced hepatic injury
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 4
  start-page: e1
  year: 2005
  ident: bib0190
  article-title: Wound healing of cutaneous sulfur mustard injuries: strategies for the development of improved therapies
  publication-title: J. Burns Wounds
– volume: 47
  start-page: 1640
  year: 2009
  end-page: 1651
  ident: bib0510
  article-title: Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice
  publication-title: Free Radic. Biol. Med.
– volume: 117
  start-page: 1566
  year: 2001
  end-page: 1573
  ident: bib0630
  article-title: PARP determines the mode of cell death in skin fibroblasts, but not keratinocytes, exposed to sulfur mustard
  publication-title: J. Invest. Dermatol.
– volume: 31
  start-page: 1607
  year: 2011
  end-page: 1617
  ident: bib0180
  article-title: NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells
  publication-title: Anticancer Res.
– volume: 263
  start-page: 12
  year: 2009
  end-page: 19
  ident: bib0300
  article-title: Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering
  publication-title: Toxicology
– volume: 38
  start-page: 119
  year: 1986
  end-page: 125
  ident: bib0380
  article-title: DNA modification by sulfur mustards and nitrosoureas and repair of these lesions
  publication-title: Basic Life Sci.
– volume: 58
  start-page: 153
  year: 2000
  end-page: 160
  ident: bib0605
  article-title: Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations
  publication-title: Toxicol. Sci.
– volume: 18
  start-page: 610
  year: 2017
  end-page: 621
  ident: bib0610
  article-title: The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
  publication-title: Nat. Rev. Mol. Cell Biol.
– volume: 6
  start-page: 245
  year: 1992
  end-page: 251
  ident: bib0480
  article-title: Concentration- and time-related effects of sulphur mustard on human epidermal keratinocyte function
  publication-title: Toxicol. in Vitro
– volume: 9
  start-page: 9772
  year: 2019
  ident: bib0110
  article-title: Safety and metabolism of long-term administration of NIAGEN (Nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults
  publication-title: Sci. Rep.
– volume: 158
  start-page: 962
  year: 2017
  end-page: 972
  ident: bib0210
  article-title: Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats
  publication-title: Pain
– volume: 149
  start-page: 202
  year: 2016
  end-page: 212
  ident: bib0765
  article-title: Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1)
  publication-title: Toxicol. Sci.
– volume: 45
  start-page: 187
  year: 2016
  end-page: 192
  ident: bib0745
  article-title: Sulfur mustard causes oxidants/antioxidants imbalance through the overexpression of free radical producing-related genes in human mustard lungs
  publication-title: Environ. Toxicol. Pharmacol.
– volume: 22
  start-page: 31
  year: 2015
  end-page: 53
  ident: bib0095
  article-title: NAD(+) metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
  publication-title: Cell Metab.
– volume: 9
  start-page: 783
  year: 2018
  ident: bib0470
  article-title: The roles of mitochondrial SIRT4 in cellular metabolism
  publication-title: Front. Endocrinol.
– volume: 1813
  start-page: 3
  year: 2018
  end-page: 8
  ident: bib0245
  article-title: Vitamin B3 in health and disease: toward the second century of discovery
  publication-title: Methods Mol. Biol. (Clifton, NJ)
– volume: 8
  start-page: 31
  year: 2010
  ident: bib0100
  article-title: PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
  publication-title: Cell Commun. Signal.: CCS
– volume: 29
  start-page: 614
  year: 2008
  end-page: 619
  ident: bib0320
  article-title: The use of melatonin to combat mustard toxicity. REVIEW
  publication-title: Neuro Endocrinol. Lett.
– volume: 91
  start-page: 39
  year: 1994
  end-page: 49
  ident: bib0385
  article-title: Detection of sulfur mustard-induced DNA modifications
  publication-title: Chem. Biol. Interact.
– volume: 17
  start-page: 533
  year: 1991
  end-page: 542
  ident: bib0835
  article-title: Niacinamide pretreatment reduces microvesicle formation in hairless guinea pigs cutaneously exposed to sulfur mustard
  publication-title: Fundam. Appl. Toxicol.
– volume: 30
  start-page: 251
  year: 2019
  end-page: 294
  ident: bib0075
  article-title: Role of nicotinamide adenine dinucleotide and related precursors as therapeutic targets for age-related degenerative diseases: rationale, biochemistry, pharmacokinetics, and outcomes
  publication-title: Antioxid. Redox Signal.
– volume: 263
  start-page: 20
  year: 2009
  end-page: 25
  ident: bib0130
  article-title: Role of poly(ADP-ribose) polymerase in sulfur mustard toxicity
  publication-title: Toxicology
– volume: 108
  start-page: 28
  year: 2011
  end-page: 33
  ident: bib0310
  article-title: Involvement of calmodulin kinase II in the action of sulphur mustard on the contraction of vascular smooth muscle
  publication-title: Basic Clin. Pharmacol. Toxicol.
– volume: 15
  start-page: S19
  year: 1996
  end-page: S31
  ident: bib0415
  article-title: In vitro studies of glucose metabolism in human epidermal keratinocytes exposed to sulfur mustard
  publication-title: Int. J. Toxicol.
– volume: 5
  start-page: 285
  year: 2005
  end-page: 296
  ident: bib0500
  article-title: Chemical approaches to the discovery and development of cancer therapies
  publication-title: Nat. Rev. Cancer
– volume: 88
  start-page: 3
  year: 2014
  end-page: 4
  ident: bib0555
  article-title: Melatonin as potential candidate to prevent the toxicity induced by chemical warfare agents
  publication-title: Arch. Toxicol.
– volume: 1203
  start-page: 92
  year: 2010
  end-page: 100
  ident: bib0345
  article-title: Oxidants and antioxidants in sulfur mustard-induced injury
  publication-title: Ann. N. Y. Acad. Sci.
– volume: 305
  start-page: 1
  year: 2016
  end-page: 11
  ident: bib0805
  article-title: Mustard vesicant-induced lung injury: advances in therapy
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 28
  start-page: 115
  year: 2008
  end-page: 130
  ident: bib0065
  article-title: Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition
  publication-title: Annu. Rev. Nutr.
– volume: 18
  start-page: 593
  year: 2004
  end-page: 599
  ident: bib0140
  article-title: An inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytes
  publication-title: Toxicol. in Vitro
– volume: 248
  start-page: 89
  year: 2010
  end-page: 99
  ident: bib0395
  article-title: Inflammatory effects of inhaled sulfur mustard in rat lung
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 14
  start-page: 149
  year: 2000
  end-page: 157
  ident: bib0645
  article-title: Effect of intracellular calcium modulation on sulfur mustard cytotoxicity in cultured human neonatal keratinocytes
  publication-title: Toxicol. in Vitro
– volume: 34
  start-page: 1168
  year: 2013
  end-page: 1201
  ident: bib0090
  article-title: Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
  publication-title: Mol. Asp. Med.
– volume: 244
  start-page: 35
  year: 2016
  end-page: 43
  ident: bib0040
  article-title: Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line
  publication-title: Toxicol. Lett.
– volume: 3
  start-page: 593
  year: 2017
  end-page: 610
  ident: bib0165
  article-title: cancer
  publication-title: Trends Cancer
– volume: 103
  start-page: 514
  year: 1967
  end-page: 527
  ident: bib0810
  article-title: The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
  publication-title: Biochem. J.
– volume: 92
  start-page: 157
  year: 2014
  end-page: 163
  ident: bib0025
  article-title: Poly(ADP-ribose): a signaling molecule in different paradigms of cell death
  publication-title: Biochem. Pharmacol.
– volume: 258
  start-page: 82
  year: 2012
  end-page: 88
  ident: bib0205
  article-title: Sulfur mustard primes human neutrophils for increased degranulation and stimulates cytokine release via TRPM2/p38 MAPK signaling
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 4
  start-page: e1890
  year: 2016
  ident: bib0370
  article-title: Effects of poly (ADP-ribose) polymerase-1 (PARP-1) inhibition on sulfur mustard-induced cutaneous injuries in vitro and in vivo
  publication-title: PeerJ
– volume: 93
  start-page: 61
  year: 2019
  end-page: 79
  ident: bib0880
  article-title: A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure
  publication-title: Arch. Toxicol.
– volume: 20
  start-page: S93
  year: 2000
  end-page: 100
  ident: bib0450
  article-title: Poly(ADP-ribose) polymerase inhibitors regulate the mechanism of sulfur mustard-initiated cell death in human lymphocytes
  publication-title: J. Appl. Toxicol.: JAT
– volume: 113
  start-page: 234
  year: 1992
  end-page: 239
  ident: bib0440
  article-title: The determination and prevention of cytotoxic effects induced in human lymphocytes by the alkylating agent 2,2’-dichlorodiethyl sulfide (sulfur mustard, HD)
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 5
  start-page: 58
  year: 2014
  end-page: 67
  ident: bib0790
  article-title: Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca(2+) signaling pathway
  publication-title: World J. Biol. Chem.
– volume: 11
  start-page: 13
  year: 2010
  end-page: 17
  ident: bib0170
  article-title: Lung carcinogenicity of sulfur mustard
  publication-title: Clin. Lung Cancer
– volume: 285
  start-page: 71
  year: 2015
  end-page: 78
  ident: bib0260
  article-title: Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 82
  start-page: 461
  year: 2008
  end-page: 470
  ident: bib0295
  article-title: Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells
  publication-title: Arch. Toxicol.
– volume: 38
  start-page: 98
  year: 2017
  end-page: 105
  ident: bib0460
  article-title: Nuclear sirtuins and inflammatory signaling pathways
  publication-title: Cytokine Growth Factor Rev.
– volume: 26
  start-page: 417
  year: 2012
  end-page: 432
  ident: bib0390
  article-title: On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
  publication-title: Genes Dev.
– volume: 38
  start-page: 9
  year: 2019
  end-page: 17
  ident: bib0045
  article-title: Role of oxidative stress and antioxidant therapy in acute and chronic phases of sulfur mustard injuries: a review
  publication-title: Cutan. Ocul. Toxicol.
– volume: 91
  start-page: 3717
  year: 2017
  end-page: 3735
  ident: bib0590
  article-title: Novel treatment opportunities for sulfur mustard-related cancers: genetic and epigenetic perspectives
  publication-title: Arch. Toxicol.
– volume: 77
  start-page: 6133
  year: 2011
  end-page: 6140
  ident: bib0870
  article-title: Determining the extremes of the cellular NAD(H) level by using an Escherichia coli NAD(+)-auxotrophic mutant
  publication-title: Appl. Environ. Microbiol.
– volume: 188
  start-page: 77
  year: 2010
  end-page: 83
  ident: bib0660
  article-title: Glutathione and malondialdehyde levels in late pulmonary complications of sulfur mustard intoxication
  publication-title: Lung
– volume: 77
  start-page: 19
  year: 2019
  end-page: 33
  ident: bib0145
  article-title: Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity
  publication-title: Cell. Mol. Life Sci.: CMLS
– volume: 4
  start-page: 491
  year: 2013
  end-page: 495
  ident: bib0655
  article-title: Sirtuin deacetylation mechanism and catalytic role of the dynamic cofactor binding loop
  publication-title: J. Phys. Chem. Lett.
– volume: 80
  start-page: 85
  year: 2019
  end-page: 92
  ident: bib0340
  article-title: Current role of mammalian sirtuins in DNA repair
  publication-title: DNA Rep.
– volume: 35
  start-page: 1018
  year: 2003
  end-page: 1027
  ident: bib0280
  article-title: Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes
  publication-title: Free Radic. Biol. Med.
– volume: 27
  start-page: 41
  year: 2008
  end-page: 53
  ident: bib0420
  article-title: The role of NAD+ depletion in the mechanism of sulfur mustard-induced metabolic injury
  publication-title: Cutan. Ocul. Toxicol.
– volume: 130
  start-page: 1095
  year: 2007
  end-page: 1107
  ident: bib0820
  article-title: Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
  publication-title: Cell
– volume: 46
  start-page: 804
  year: 2018
  end-page: 822
  ident: bib0160
  article-title: The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1
  publication-title: Nucleic Acids Res.
– start-page: 75
  year: 2006
  end-page: 90
  ident: bib0220
  article-title: PARP-1 As Novel Coactivator of NF-κB in Inflammatory Disorders. Poly(ADP-Ribosyl)ation
– volume: 328
  start-page: 732
  year: 2009
  end-page: 739
  ident: bib0185
  article-title: A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection
  publication-title: J. Pharmacol. Exp. Ther.
– volume: 119
  start-page: 197
  year: 2018
  end-page: 206
  ident: bib0535
  article-title: A review on symptoms, treatments protocols, and proteomic profile in sulfur mustard-exposed victims
  publication-title: J. Cell. Biochem.
– volume: 188
  start-page: 263
  year: 2009
  end-page: 269
  ident: bib0705
  article-title: Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes
  publication-title: Toxicol. Lett.
– volume: 47
  start-page: 119
  year: 2019
  end-page: 130
  ident: bib0725
  article-title: Keeping the balance in NAD metabolism
  publication-title: Biochem. Soc. Trans.
– volume: 552
  start-page: 187
  year: 2017
  end-page: 193
  ident: bib0690
  article-title: Enhancing mitochondrial proteostasis reduces amyloid-beta proteotoxicity
  publication-title: Nature
– volume: 15
  start-page: 133
  year: 1995
  end-page: 138
  ident: bib0850
  article-title: Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin
  publication-title: J. Appl. Toxicol.: JAT
– volume: 34
  start-page: 1046
  year: 2013
  end-page: 1065
  ident: bib0080
  article-title: Poly(ADP-ribose): PARadigms and PARadoxes
  publication-title: Mol. Asp. Med.
– volume: 280
  start-page: 21313
  year: 2005
  end-page: 21320
  ident: bib0365
  article-title: Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
  publication-title: J. Biol. Chem.
– volume: 26
  start-page: 507
  year: 2014
  end-page: 523
  ident: bib0670
  article-title: The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review
  publication-title: Inhal. Toxicol.
– volume: 7
  start-page: 12948
  year: 2016
  ident: bib0760
  article-title: Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
  publication-title: Nat. Commun.
– volume: 128
  start-page: 1626
  year: 2008
  end-page: 1632
  ident: bib0615
  article-title: Role of NF-kappaB/RelA and MAPK pathways in keratinocytes in response to sulfur mustard
  publication-title: J. Invest. Dermatol.
– volume: 81
  start-page: 85
  year: 1985
  end-page: 90
  ident: bib0195
  article-title: Sulfur mustard lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to athymic nude mice
  publication-title: Toxicol. Appl. Pharmacol.
– volume: 42
  start-page: 393
  year: 1994
  end-page: 405
  ident: bib0360
  article-title: Failure to observe a relationship between bis-(beta-chloroethyl)sulfide-induced NAD depletion and cytotoxicity in the rat keratinocyte culture
  publication-title: J. Toxicol. Environ. Health
– volume: 263
  start-page: 41
  year: 2009
  end-page: 46
  ident: bib0020
  article-title: Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury
  publication-title: Toxicology
– volume: 294
  start-page: 9295
  year: 2019
  end-page: 9307
  ident: bib0825
  article-title: Dihydronicotinamide riboside is a potent NAD(+) concentration enhancer in vitro and in vivo
  publication-title: J. Biol. Chem.
– volume: 1864
  start-page: 2036
  year: 2017
  end-page: 2042
  ident: bib0155
  article-title: Matrix metalloproteinases as regulators of inflammatory processes
  publication-title: Biochim. Biophys. Acta Mol. Cell Res.
– volume: 12
  start-page: 147
  year: 1996
  end-page: 153
  ident: bib0435
  article-title: The time-dependent effect of 2,2’-dichlorodiethyl sulfide (sulfur mustard, HD, 1,1’-thiobis [2-chloroethane]) on the lymphocyte viability and the kinetics of protection by poly(ADP-ribose) polymerase inhibitors
  publication-title: Cell Biol. Toxicol.
– volume: 28
  start-page: 251
  year: 2018
  end-page: 272
  ident: bib0815
  article-title: NAD(H) and NADP(H) redox couples and cellular energy metabolism
  publication-title: Antioxid. Redox Signal.
– volume: 10
  start-page: 1187
  year: 2019
  ident: bib0230
  article-title: The multi-faceted ecto-enzyme CD38: roles in immunomodulation, cancer, aging, and metabolic diseases
  publication-title: Front. Immunol.
– volume: 1854
  start-page: 1132
  year: 2015
  end-page: 1137
  ident: bib0200
  article-title: Calcium mobilizing second messengers derived from NAD
  publication-title: Biochim. Biophys. Acta
– volume: 20
  start-page: 15
  year: 2014
  end-page: 30
  ident: bib0325
  article-title: Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human
  publication-title: Antioxid. Redox Signal.
– volume: 39
  start-page: 109
  year: 1987
  end-page: 122
  ident: bib0445
  article-title: 2,2’-Dichlorodiethyl sulfide (sulfur mustard) decreases NAD+ levels in human leukocytes
  publication-title: Toxicol. Lett.
– volume: 312
  start-page: 109
  year: 2019
  end-page: 117
  ident: bib0780
  article-title: Evaluation of selective and non-selective cyclooxygenase inhibitors on sulfur mustard-induced pro-inflammatory cytokine formation in normal human epidermal keratinocytes
  publication-title: Toxicol. Lett.
– volume: 1863
  start-page: 1761
  year: 2017
  end-page: 1769
  ident: bib0475
  article-title: Role of PARP-1 as a novel transcriptional regulator of MMP-9 in diabetic retinopathy
  publication-title: Biochim. Biophys. Acta Mol. Basis Dis.
– volume: 40
  start-page: 290
  year: 2018
  end-page: 296
  ident: bib0350
  article-title: Sulfur mustard triggers oxidative stress through glutathione depletion and altered expression of glutathione-related enzymes in human airways
  publication-title: Immunopharmacol. Immunotoxicol.
– volume: 219c
  start-page: 143
  year: 2014
  end-page: 150
  ident: bib0710
  article-title: Chlorambucil (nitrogen mustard) induced impairment of early vascular endothelial cell migration - effects of alpha-linolenic acid and N-acetylcysteine
  publication-title: Chem. Biol. Interact.
– volume: 54
  start-page: 212
  year: 2000
  end-page: 221
  ident: bib0600
  article-title: Protection from cytotoxic effects induced by the nitrogen mustard mechlorethamine on human bronchial epithelial cells in vitro
  publication-title: Toxicol. Sci.
– start-page: 1
  year: 2016
  end-page: 30
  ident: bib0695
  article-title: Sulfur mustard
  publication-title: Critical Care Toxicology
– volume: 14
  start-page: 1179
  year: 2007
  end-page: 1187
  ident: bib0010
  article-title: Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation
  publication-title: Curr. Med. Chem.
– volume: 9
  start-page: 269
  year: 1993
  end-page: 277
  ident: bib0120
  article-title: Sulfur mustard-increased proteolysis following in vitro and in vivo exposures
  publication-title: Cell Biol. Toxicol.
– volume: 156
  start-page: 17
  year: 1999
  ident: 10.1016/j.toxlet.2020.01.024_bib0225
  article-title: Activation of poly [ADP-Ribose] polymerase in endothelial cells and keratinocytes: role in an in vitro model of sulfur mustard-mediated vesication
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1006/taap.1999.8634
– volume: 81
  start-page: 85
  year: 1985
  ident: 10.1016/j.toxlet.2020.01.024_bib0195
  article-title: Sulfur mustard lowers nicotinamide adenine dinucleotide concentrations in human skin grafted to athymic nude mice
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/0041-008X(85)90123-1
– volume: 107
  start-page: 439
  year: 1991
  ident: 10.1016/j.toxlet.2020.01.024_bib0495
  article-title: Effects of nicotinamide on biochemical changes and microblistering induced by sulfur mustard in human skin organ cultures
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/0041-008X(91)90307-Z
– volume: 13
  start-page: 93
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0525
  article-title: Effects of curcuminoids-piperine combination on systemic oxidative stress, clinical symptoms and quality of life in subjects with chronic pulmonary complications due to sulfur mustard: a randomized controlled trial
  publication-title: J. Diet. Suppl.
  doi: 10.3109/19390211.2014.952865
– volume: 34
  start-page: 1046
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0080
  article-title: Poly(ADP-ribose): PARadigms and PARadoxes
  publication-title: Mol. Asp. Med.
  doi: 10.1016/j.mam.2012.12.010
– volume: 285
  start-page: 71
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0260
  article-title: Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2015.03.009
– volume: 733
  start-page: 14
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0315
  article-title: Niacin requirements for genomic stability
  publication-title: Mutat. Res.
  doi: 10.1016/j.mrfmmm.2011.11.008
– volume: 26
  start-page: 507
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0670
  article-title: The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review
  publication-title: Inhal. Toxicol.
  doi: 10.3109/08958378.2014.920439
– volume: 91
  start-page: 2179
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0720
  article-title: N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-016-1873-x
– volume: 235
  start-page: 161
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0335
  article-title: Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2015.04.006
– volume: 80
  start-page: 85
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0340
  article-title: Current role of mammalian sirtuins in DNA repair
  publication-title: DNA Rep.
  doi: 10.1016/j.dnarep.2019.06.009
– volume: 47
  start-page: 119
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0725
  article-title: Keeping the balance in NAD metabolism
  publication-title: Biochem. Soc. Trans.
  doi: 10.1042/BST20180417
– volume: 9
  start-page: 1453
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0105
  article-title: Therapeutic potential of nitrogen mustard based hybrid molecules
  publication-title: Front. Pharmacol.
  doi: 10.3389/fphar.2018.01453
– volume: 15
  start-page: S19
  issue: Suppl. 2
  year: 1996
  ident: 10.1016/j.toxlet.2020.01.024_bib0415
  article-title: In vitro studies of glucose metabolism in human epidermal keratinocytes exposed to sulfur mustard
  publication-title: Int. J. Toxicol.
  doi: 10.3109/10915819609048334
– volume: 39
  start-page: 362
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0505
  article-title: Pro-oxidant-antioxidant balance in Iranian veterans with sulfur mustard toxicity and different levels of pulmonary disorders
  publication-title: Drug Chem. Toxicol.
  doi: 10.3109/01480545.2015.1122033
– volume: 117
  start-page: 1566
  year: 2001
  ident: 10.1016/j.toxlet.2020.01.024_bib0630
  article-title: PARP determines the mode of cell death in skin fibroblasts, but not keratinocytes, exposed to sulfur mustard
  publication-title: J. Invest. Dermatol.
  doi: 10.1046/j.0022-202x.2001.01578.x
– volume: 7
  start-page: 9433
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0465
  article-title: Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-017-09648-6
– volume: 38
  start-page: 119
  year: 1986
  ident: 10.1016/j.toxlet.2020.01.024_bib0380
  article-title: DNA modification by sulfur mustards and nitrosoureas and repair of these lesions
  publication-title: Basic Life Sci.
– volume: 22
  start-page: 31
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0095
  article-title: NAD(+) metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2015.05.023
– volume: 48
  start-page: 184
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0255
  article-title: Evaluation of plasma, erythrocytes, and bronchoalveolar lavage fluid antioxidant defense system in sulfur mustard-injured patients
  publication-title: Clin. Toxicol. (Phila. Pa)
  doi: 10.3109/15563651003623297
– volume: 258
  start-page: 82
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0205
  article-title: Sulfur mustard primes human neutrophils for increased degranulation and stimulates cytokine release via TRPM2/p38 MAPK signaling
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2011.10.010
– volume: 305
  start-page: 1
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0805
  article-title: Mustard vesicant-induced lung injury: advances in therapy
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2016.05.014
– volume: 3
  start-page: 593
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0165
  article-title: cancer
  publication-title: Trends Cancer
  doi: 10.1016/j.trecan.2017.06.001
– volume: 38
  start-page: 98
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0460
  article-title: Nuclear sirtuins and inflammatory signaling pathways
  publication-title: Cytokine Growth Factor Rev.
  doi: 10.1016/j.cytogfr.2017.11.001
– volume: 20
  start-page: 15
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0325
  article-title: Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human
  publication-title: Antioxid. Redox Signal.
  doi: 10.1089/ars.2012.5082
– volume: 1863
  start-page: 1761
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0475
  article-title: Role of PARP-1 as a novel transcriptional regulator of MMP-9 in diabetic retinopathy
  publication-title: Biochim. Biophys. Acta Mol. Basis Dis.
  doi: 10.1016/j.bbadis.2017.04.024
– volume: 1813
  start-page: 3
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0245
  article-title: Vitamin B3 in health and disease: toward the second century of discovery
  publication-title: Methods Mol. Biol. (Clifton, NJ)
  doi: 10.1007/978-1-4939-8588-3_1
– volume: 141
  start-page: 483
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0515
  article-title: Mitohormesis and metabolic health: the interplay between ROS, cAMP and sirtuins
  publication-title: Free Radic. Biol. Med.
  doi: 10.1016/j.freeradbiomed.2019.07.017
– volume: 206
  start-page: 496
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0035
  article-title: Silibinin as a potential therapeutic for sulfur mustard injuries
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/j.cbi.2013.06.010
– volume: 38
  start-page: 9
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0045
  article-title: Role of oxidative stress and antioxidant therapy in acute and chronic phases of sulfur mustard injuries: a review
  publication-title: Cutan. Ocul. Toxicol.
  doi: 10.1080/15569527.2018.1495230
– volume: 314
  start-page: H839
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0425
  article-title: Emerging potential benefits of modulating NAD(+) metabolism in cardiovascular disease
  publication-title: Am. J. Physiol. Heart Circ. Physiol.
  doi: 10.1152/ajpheart.00409.2017
– volume: 14
  start-page: 253
  year: 1990
  ident: 10.1016/j.toxlet.2020.01.024_bib0545
  article-title: Ultrastructural correlates of the protection afforded by niacinamide against sulfur mustard-induced cytotoxicity of human lymphocytes in vitro
  publication-title: Ultrastruct. Pathol.
  doi: 10.3109/01913129009076129
– volume: 12
  start-page: 147
  year: 1996
  ident: 10.1016/j.toxlet.2020.01.024_bib0435
  article-title: The time-dependent effect of 2,2’-dichlorodiethyl sulfide (sulfur mustard, HD, 1,1’-thiobis [2-chloroethane]) on the lymphocyte viability and the kinetics of protection by poly(ADP-ribose) polymerase inhibitors
  publication-title: Cell Biol. Toxicol.
  doi: 10.1007/BF00148168
– volume: 118
  start-page: 3549
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0530
  article-title: Ocular effects of sulfur mustard and therapeutic approaches
  publication-title: J. Cell. Biochem.
  doi: 10.1002/jcb.25892
– volume: 14
  start-page: 1179
  year: 2007
  ident: 10.1016/j.toxlet.2020.01.024_bib0010
  article-title: Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation
  publication-title: Curr. Med. Chem.
  doi: 10.2174/092986707780597998
– volume: 113
  start-page: 234
  year: 1992
  ident: 10.1016/j.toxlet.2020.01.024_bib0440
  article-title: The determination and prevention of cytotoxic effects induced in human lymphocytes by the alkylating agent 2,2’-dichlorodiethyl sulfide (sulfur mustard, HD)
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/0041-008X(92)90119-D
– volume: 27
  start-page: 408
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0575
  article-title: Changes in the oxidative stress/anti-oxidant system after exposure to sulfur mustard and antioxidant strategies in the therapy, a review
  publication-title: Toxicol. Mech. Methods
  doi: 10.1080/15376516.2017.1320695
– volume: 263
  start-page: 26
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0620
  article-title: Matrix metalloproteinase-9 expression and release from skin fibroblasts interacting with keratinocytes: upregulation in response to sulphur mustard
  publication-title: Toxicology
  doi: 10.1016/j.tox.2008.08.011
– volume: 18
  start-page: 610
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0610
  article-title: The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
  publication-title: Nat. Rev. Mol. Cell Biol.
  doi: 10.1038/nrm.2017.53
– volume: 5
  start-page: 95
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0175
  article-title: Late respiratory effects of sulfur mustard: how is the early symptoms severity involved?
  publication-title: Chron. Respir. Dis.
  doi: 10.1177/1479972307087191
– volume: 134
  start-page: 1
  year: 2001
  ident: 10.1016/j.toxlet.2020.01.024_bib0330
  article-title: Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/S0009-2797(00)00209-X
– volume: 20
  start-page: S93
  issue: Suppl 1
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0450
  article-title: Poly(ADP-ribose) polymerase inhibitors regulate the mechanism of sulfur mustard-initiated cell death in human lymphocytes
  publication-title: J. Appl. Toxicol.: JAT
  doi: 10.1002/1099-1263(200012)20:1+<::AID-JAT664>3.3.CO;2-D
– volume: 28
  start-page: 251
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0815
  article-title: NAD(H) and NADP(H) redox couples and cellular energy metabolism
  publication-title: Antioxid. Redox Signal.
  doi: 10.1089/ars.2017.7216
– volume: 263
  start-page: 20
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0130
  article-title: Role of poly(ADP-ribose) polymerase in sulfur mustard toxicity
  publication-title: Toxicology
  doi: 10.1016/j.tox.2008.06.002
– volume: 88
  start-page: 1909
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0405
  article-title: Chemical warfare in the First World War: reflections 100 years later
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-014-1370-z
– volume: 225
  start-page: 20
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0265
  article-title: Nicotinamide riboside protects against liver fibrosis induced by CCl4 via regulating the acetylation of Smads signaling pathway
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2019.03.064
– volume: 46
  start-page: 804
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0160
  article-title: The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkx1205
– volume: 39
  start-page: 109
  year: 1987
  ident: 10.1016/j.toxlet.2020.01.024_bib0445
  article-title: 2,2’-Dichlorodiethyl sulfide (sulfur mustard) decreases NAD+ levels in human leukocytes
  publication-title: Toxicol. Lett.
  doi: 10.1016/0378-4274(87)90263-3
– volume: 312
  start-page: 109
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0780
  article-title: Evaluation of selective and non-selective cyclooxygenase inhibitors on sulfur mustard-induced pro-inflammatory cytokine formation in normal human epidermal keratinocytes
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2019.03.012
– volume: 34
  start-page: 1168
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0090
  article-title: Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
  publication-title: Mol. Asp. Med.
  doi: 10.1016/j.mam.2013.01.004
– volume: 82
  start-page: 461
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0295
  article-title: Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-007-0265-7
– volume: 100
  start-page: 85
  year: 1996
  ident: 10.1016/j.toxlet.2020.01.024_bib0485
  article-title: Ca2+ homeostasis and Ca2+ signalling in sulphur mustard-exposed normal human epidermal keratinocytes
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/S0009-2797(96)03692-7
– volume: 6
  start-page: 245
  year: 1992
  ident: 10.1016/j.toxlet.2020.01.024_bib0480
  article-title: Concentration- and time-related effects of sulphur mustard on human epidermal keratinocyte function
  publication-title: Toxicol. in Vitro
  doi: 10.1016/0887-2333(92)90038-S
– volume: 92
  start-page: 157
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0025
  article-title: Poly(ADP-ribose): a signaling molecule in different paradigms of cell death
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2014.06.021
– volume: 42
  start-page: 393
  year: 1994
  ident: 10.1016/j.toxlet.2020.01.024_bib0360
  article-title: Failure to observe a relationship between bis-(beta-chloroethyl)sulfide-induced NAD depletion and cytotoxicity in the rat keratinocyte culture
  publication-title: J. Toxicol. Environ. Health
  doi: 10.1080/15287399409531890
– volume: 10
  start-page: 1187
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0230
  article-title: The multi-faceted ecto-enzyme CD38: roles in immunomodulation, cancer, aging, and metabolic diseases
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.01187
– volume: 2012
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0400
  article-title: Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation
  publication-title: Oxid. Med. Cell. Longev.
  doi: 10.1155/2012/321653
– volume: 244
  start-page: 35
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0040
  article-title: Protective effects of the thiol compounds GSH and NAC against sulfur mustard toxicity in a human keratinocyte cell line
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2015.09.002
– volume: 15
  start-page: 133
  year: 1995
  ident: 10.1016/j.toxlet.2020.01.024_bib0850
  article-title: Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin
  publication-title: J. Appl. Toxicol.: JAT
  doi: 10.1002/jat.2550150213
– volume: 11
  start-page: 13
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0170
  article-title: Lung carcinogenicity of sulfur mustard
  publication-title: Clin. Lung Cancer
  doi: 10.3816/CLC.2010.n.002
– volume: 77
  start-page: 6133
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0870
  article-title: Determining the extremes of the cellular NAD(H) level by using an Escherichia coli NAD(+)-auxotrophic mutant
  publication-title: Appl. Environ. Microbiol.
  doi: 10.1128/AEM.00630-11
– volume: 34
  start-page: 85
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0565
  article-title: Oxidative stress after sulfur mustard intoxication and its reduction by melatonin: efficacy of antioxidant therapy during serious intoxication
  publication-title: Drug Chem. Toxicol.
  doi: 10.3109/01480545.2010.505238
– volume: 4
  start-page: e1890
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0370
  article-title: Effects of poly (ADP-ribose) polymerase-1 (PARP-1) inhibition on sulfur mustard-induced cutaneous injuries in vitro and in vivo
  publication-title: PeerJ
  doi: 10.7717/peerj.1890
– volume: 245
  start-page: 352
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0055
  article-title: Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2010.04.001
– volume: 37
  start-page: 332
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0305
  article-title: Acute intensive care unit management of mustard gas victims: the Turkish experience
  publication-title: Cutan. Ocul. Toxicol.
  doi: 10.1080/15569527.2018.1464018
– volume: 91
  start-page: 3717
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0590
  article-title: Novel treatment opportunities for sulfur mustard-related cancers: genetic and epigenetic perspectives
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-017-2086-7
– volume: 27
  start-page: 529
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0595
  article-title: Therapeutic potential of NAD-boosting molecules: the in vivo evidence
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2018.02.011
– start-page: 1
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0695
  article-title: Sulfur mustard
– volume: 286
  start-page: 111
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0730
  article-title: Advanced biotherapy for the treatment of sulfur mustard poisoning
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/j.cbi.2018.03.011
– volume: 26
  start-page: 417
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0390
  article-title: On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
  publication-title: Genes Dev.
  doi: 10.1101/gad.183509.111
– volume: 367
  start-page: 1
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0865
  article-title: Protective effects of polydatin against sulfur mustard-induced hepatic injury
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2019.01.013
– volume: 248
  start-page: 89
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0395
  article-title: Inflammatory effects of inhaled sulfur mustard in rat lung
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2010.07.018
– volume: 111
  start-page: 64
  year: 1998
  ident: 10.1016/j.toxlet.2020.01.024_bib0625
  article-title: Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway
  publication-title: J. Invest. Dermatol.
  doi: 10.1046/j.1523-1747.1998.00250.x
– volume: 54
  start-page: 212
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0600
  article-title: Protection from cytotoxic effects induced by the nitrogen mustard mechlorethamine on human bronchial epithelial cells in vitro
  publication-title: Toxicol. Sci.
  doi: 10.1093/toxsci/54.1.212
– volume: 24
  start-page: 1747
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0755
  article-title: RUNX poly(ADP-ribosyl)ation and BLM interaction facilitate the fanconi anemia pathway of DNA repair
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2018.07.038
– volume: 293
  start-page: 51
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0635
  article-title: Sulfur mustard resistant keratinocytes obtained elevated glutathione levels and other changes in the antioxidative defense mechanism
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2017.11.024
– volume: 4
  start-page: 491
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0655
  article-title: Sirtuin deacetylation mechanism and catalytic role of the dynamic cofactor binding loop
  publication-title: J. Phys. Chem. Lett.
  doi: 10.1021/jz302015s
– volume: 263
  start-page: 12
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0300
  article-title: Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering
  publication-title: Toxicology
  doi: 10.1016/j.tox.2009.01.019
– volume: 19
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0355
  article-title: Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments
  publication-title: EMBO Rep.
  doi: 10.15252/embr.201846263
– volume: 120
  start-page: 120
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0125
  article-title: Investigating prevalence and pattern of long-term cardiovascular disorders in sulphur mustard-exposed victims and determining proper biomarkers for early defining, monitoring and analysis of patients’ feedback on therapy
  publication-title: Basic Clin. Pharmacol. Toxicol.
  doi: 10.1111/bcpt.12666
– volume: 20
  start-page: S129
  issue: Suppl 1
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0015
  article-title: Treatment of sulfur mustard (HD)-induced lung injury
  publication-title: J. Appl. Toxicol.: JAT
– volume: 9
  start-page: 269
  year: 1993
  ident: 10.1016/j.toxlet.2020.01.024_bib0120
  article-title: Sulfur mustard-increased proteolysis following in vitro and in vivo exposures
  publication-title: Cell Biol. Toxicol.
  doi: 10.1007/BF00755605
– volume: 88
  start-page: 3
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0555
  article-title: Melatonin as potential candidate to prevent the toxicity induced by chemical warfare agents
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-013-1111-8
– volume: 18
  start-page: 593
  year: 2004
  ident: 10.1016/j.toxlet.2020.01.024_bib0140
  article-title: An inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytes
  publication-title: Toxicol. in Vitro
  doi: 10.1016/j.tiv.2004.01.009
– volume: 9
  start-page: 783
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0470
  article-title: The roles of mitochondrial SIRT4 in cellular metabolism
  publication-title: Front. Endocrinol.
  doi: 10.3389/fendo.2018.00783
– volume: 244
  start-page: 112
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0715
  article-title: Medical documentation, bioanalytical evidence of an accidental human exposure to sulfur mustard and general therapy recommendations
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2015.08.1105
– volume: 128
  start-page: 1626
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0615
  article-title: Role of NF-kappaB/RelA and MAPK pathways in keratinocytes in response to sulfur mustard
  publication-title: J. Invest. Dermatol.
  doi: 10.1038/sj.jid.5701234
– volume: 14
  start-page: 149
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0645
  article-title: Effect of intracellular calcium modulation on sulfur mustard cytotoxicity in cultured human neonatal keratinocytes
  publication-title: Toxicol. in Vitro
  doi: 10.1016/S0887-2333(00)00005-9
– volume: 58
  start-page: 153
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0605
  article-title: Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations
  publication-title: Toxicol. Sci.
  doi: 10.1093/toxsci/58.1.153
– volume: 27
  start-page: 659
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0735
  article-title: Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection
  publication-title: Inhal. Toxicol.
  doi: 10.3109/08958378.2015.1092184
– volume: 158
  start-page: 962
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0210
  article-title: Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats
  publication-title: Pain
  doi: 10.1097/j.pain.0000000000000862
– volume: 244
  start-page: 56
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0410
  article-title: Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2015.09.010
– volume: 1854
  start-page: 1132
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0200
  article-title: Calcium mobilizing second messengers derived from NAD
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbapap.2014.12.015
– volume: 23
  start-page: 209
  year: 2007
  ident: 10.1016/j.toxlet.2020.01.024_bib0215
  article-title: Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity
  publication-title: Toxicol. Ind. Health
  doi: 10.1177/0748233707083541
– volume: 293
  start-page: 91
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0455
  article-title: Effects of anti-inflammatory compounds on sulfur mustard injured cells: recommendations and caveats suggested by in vitro cell culture models
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2017.09.003
– volume: 28
  start-page: 643
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0680
  article-title: The role of sirtuins in antioxidant and redox signaling
  publication-title: Antioxid. Redox Signal.
  doi: 10.1089/ars.2017.7290
– volume: 28
  start-page: 115
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0065
  article-title: Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition
  publication-title: Annu. Rev. Nutr.
  doi: 10.1146/annurev.nutr.28.061807.155443
– volume: 36
  start-page: 270
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0570
  article-title: Sulfur mustard causes oxidative stress and depletion of antioxidants in muscles, livers, and kidneys of Wistar rats
  publication-title: Drug Chem. Toxicol.
  doi: 10.3109/01480545.2012.710629
– volume: 27
  start-page: 41
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0420
  article-title: The role of NAD+ depletion in the mechanism of sulfur mustard-induced metabolic injury
  publication-title: Cutan. Ocul. Toxicol.
  doi: 10.1080/15569520701863696
– volume: 35
  start-page: 1018
  year: 2003
  ident: 10.1016/j.toxlet.2020.01.024_bib0280
  article-title: Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes
  publication-title: Free Radic. Biol. Med.
  doi: 10.1016/S0891-5849(03)00439-8
– volume: 233
  start-page: 488
  year: 1958
  ident: 10.1016/j.toxlet.2020.01.024_bib0580
  article-title: Biosynthesis of diphosphopyridine nucleotide. I. Identification of intermediates
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)64789-1
– volume: 178
  start-page: 946
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0030
  article-title: Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases
  publication-title: Am. J. Pathol.
  doi: 10.1016/j.ajpath.2010.12.004
– volume: 71
  start-page: 243
  year: 1997
  ident: 10.1016/j.toxlet.2020.01.024_bib0135
  article-title: Effect of sulphur mustard on the expression of urokinase in cultured 3T3 fibroblasts
  publication-title: Arch. Toxicol.
  doi: 10.1007/s002040050383
– volume: 5
  start-page: 58
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0790
  article-title: Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca(2+) signaling pathway
  publication-title: World J. Biol. Chem.
  doi: 10.4331/wjbc.v5.i1.58
– volume: 34
  start-page: 706
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0750
  article-title: Serum albumin and paraoxonase activity in Iranian veterans 20 years after sulfur mustard exposure
  publication-title: Immunopharmacol. Immunotoxicol.
  doi: 10.3109/08923973.2011.638306
– volume: 16
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0665
  article-title: Serum matrix metalloproteinase levels in patients exposed to sulfur mustard
  publication-title: Iran. Red Crescent Med. J.
  doi: 10.5812/ircmj.15129
– volume: 30
  start-page: 483
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0285
  article-title: Altered levels of GST activity, Vit C, TPX and Cu in individuals with long-term sulfur mustard-induced lung complications
  publication-title: Inhal. Toxicol.
  doi: 10.1080/08958378.2018.1545809
– volume: 65
  start-page: 567
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0520
  article-title: Short-term curcuminoid supplementation for chronic pulmonary complications due to sulfur mustard intoxication: positive results of a randomized double-blind placebo-controlled trial
  publication-title: Drug Res.
– volume: 255
  start-page: 176
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0005
  article-title: Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2011.06.012
– volume: 72
  start-page: 153
  year: 1992
  ident: 10.1016/j.toxlet.2020.01.024_bib0150
  article-title: Free radical-mediated lung response to the monofunctional sulfur mustard butyl 2-chloroethyl sulfide after subcutaneous injection
  publication-title: Toxicology
  doi: 10.1016/0300-483X(92)90109-R
– volume: 188
  start-page: 77
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0660
  article-title: Glutathione and malondialdehyde levels in late pulmonary complications of sulfur mustard intoxication
  publication-title: Lung
  doi: 10.1007/s00408-009-9178-y
– volume: 4
  start-page: e1
  year: 2005
  ident: 10.1016/j.toxlet.2020.01.024_bib0190
  article-title: Wound healing of cutaneous sulfur mustard injuries: strategies for the development of improved therapies
  publication-title: J. Burns Wounds
– volume: 7
  start-page: 12948
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0760
  article-title: Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms12948
– volume: 112
  start-page: 1386
  year: 2015
  ident: 10.1016/j.toxlet.2020.01.024_bib0375
  article-title: NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1417290112
– volume: 5
  start-page: 285
  year: 2005
  ident: 10.1016/j.toxlet.2020.01.024_bib0500
  article-title: Chemical approaches to the discovery and development of cancer therapies
  publication-title: Nat. Rev. Cancer
  doi: 10.1038/nrc1587
– volume: 263
  start-page: 41
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0020
  article-title: Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury
  publication-title: Toxicology
  doi: 10.1016/j.tox.2008.08.025
– volume: 29
  start-page: 614
  year: 2008
  ident: 10.1016/j.toxlet.2020.01.024_bib0320
  article-title: The use of melatonin to combat mustard toxicity. REVIEW
  publication-title: Neuro Endocrinol. Lett.
– volume: 15
  start-page: 838
  year: 2012
  ident: 10.1016/j.toxlet.2020.01.024_bib0085
  article-title: The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2012.04.022
– volume: 1
  start-page: 28
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0430
  article-title: The injury progression of T lymphocytes in a mouse model with subcutaneous injection of a high dose of sulfur mustard
  publication-title: Mil. Med. Res.
– volume: 30
  start-page: 251
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0075
  article-title: Role of nicotinamide adenine dinucleotide and related precursors as therapeutic targets for age-related degenerative diseases: rationale, biochemistry, pharmacokinetics, and outcomes
  publication-title: Antioxid. Redox Signal.
  doi: 10.1089/ars.2017.7269
– volume: 26
  start-page: 239
  year: 2006
  ident: 10.1016/j.toxlet.2020.01.024_bib0650
  article-title: Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure
  publication-title: J. Appl. Toxicol.: JAT
  doi: 10.1002/jat.1134
– volume: 6
  start-page: 285
  year: 1990
  ident: 10.1016/j.toxlet.2020.01.024_bib0685
  article-title: The use of human epidermal keratinocytes in culture as a model for studying the biochemical mechanisms of sulfur mustard toxicity
  publication-title: Cell Biol. Toxicol.
  doi: 10.1007/BF02443803
– volume: 93
  start-page: 61
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0880
  article-title: A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-018-2324-7
– volume: 77
  start-page: 19
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0145
  article-title: Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity
  publication-title: Cell. Mol. Life Sci.: CMLS
  doi: 10.1007/s00018-019-03366-0
– volume: 3
  start-page: 393
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0270
  article-title: Sulfur mustard-stimulated proteases and their inhibitors in a cultured normal human epidermal keratinocytes model: a potential approach for anti-vesicant drug development
  publication-title: Toxicol. Rep.
  doi: 10.1016/j.toxrep.2016.03.007
– volume: 27
  start-page: 513
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0830
  article-title: NAD(+) intermediates: the biology and therapeutic potential of NMN and NR
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2017.11.002
– volume: 35
  start-page: 208
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0560
  article-title: Selection of non-steroidal anti-inflammatory drug and treatment regimen for sulfur mustard-induced cutaneous lesions
  publication-title: Cutan. Ocul. Toxicol.
  doi: 10.3109/15569527.2015.1076436
– volume: 294
  start-page: 9295
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0825
  article-title: Dihydronicotinamide riboside is a potent NAD(+) concentration enhancer in vitro and in vivo
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA118.005772
– volume: 8
  start-page: 31
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0100
  article-title: PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
  publication-title: Cell Commun. Signal.: CCS
  doi: 10.1186/1478-811X-8-31
– volume: 25
  start-page: 167
  year: 1995
  ident: 10.1016/j.toxlet.2020.01.024_bib0050
  article-title: Biological fate of sulphur mustard, 1,1’-thiobis(2-chloroethane): identification of beta-lyase metabolites and hydrolysis products in human urine
  publication-title: Xenobiotica
  doi: 10.3109/00498259509061842
– volume: 25
  start-page: 1939
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0290
  article-title: Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders
  publication-title: Cell. Signal.
  doi: 10.1016/j.cellsig.2013.06.007
– volume: 14
  start-page: 3834
  year: 2013
  ident: 10.1016/j.toxlet.2020.01.024_bib0640
  article-title: Crosstalk between oxidative stress and SIRT1: impact on the aging process
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms14023834
– volume: 103
  start-page: 514
  year: 1967
  ident: 10.1016/j.toxlet.2020.01.024_bib0810
  article-title: The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
  publication-title: Biochem. J.
  doi: 10.1042/bj1030514
– volume: 55
  start-page: 68
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0860
  article-title: Early oxidative stress, DNA damage and inflammation resulting from subcutaneous injection of sulfur mustard into mice
  publication-title: Environ. Toxicol. Pharmacol.
  doi: 10.1016/j.etap.2017.06.016
– volume: 13
  start-page: 99
  year: 2000
  ident: 10.1016/j.toxlet.2020.01.024_bib0060
  article-title: Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists
  publication-title: In Vitro Mol. Toxicol.
  doi: 10.1089/109793300440695
– volume: 293
  start-page: 77
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0275
  article-title: Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2017.11.005
– volume: 1864
  start-page: 2036
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0155
  article-title: Matrix metalloproteinases as regulators of inflammatory processes
  publication-title: Biochim. Biophys. Acta Mol. Cell Res.
  doi: 10.1016/j.bbamcr.2017.05.010
– volume: 52
  start-page: 12
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0800
  article-title: The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation
  publication-title: DNA Rep.
  doi: 10.1016/j.dnarep.2017.02.001
– volume: 149
  start-page: 202
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0765
  article-title: Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1)
  publication-title: Toxicol. Sci.
  doi: 10.1093/toxsci/kfv226
– start-page: 141
  year: 2006
  ident: 10.1016/j.toxlet.2020.01.024_bib0775
– volume: 80
  start-page: 1103
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0795
  article-title: Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2010.06.010
– volume: 219c
  start-page: 143
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0710
  article-title: Chlorambucil (nitrogen mustard) induced impairment of early vascular endothelial cell migration - effects of alpha-linolenic acid and N-acetylcysteine
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/j.cbi.2014.05.015
– volume: 552
  start-page: 187
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0690
  article-title: Enhancing mitochondrial proteostasis reduces amyloid-beta proteotoxicity
  publication-title: Nature
  doi: 10.1038/nature25143
– volume: 47
  start-page: 1640
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0510
  article-title: Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice
  publication-title: Free Radic. Biol. Med.
  doi: 10.1016/j.freeradbiomed.2009.09.011
– volume: 227
  start-page: 21
  year: 2006
  ident: 10.1016/j.toxlet.2020.01.024_bib0675
  article-title: Calmodulin mediates sulfur mustard toxicity in human keratinocytes
  publication-title: Toxicology
  doi: 10.1016/j.tox.2006.06.019
– volume: 17
  start-page: 533
  year: 1991
  ident: 10.1016/j.toxlet.2020.01.024_bib0835
  article-title: Niacinamide pretreatment reduces microvesicle formation in hairless guinea pigs cutaneously exposed to sulfur mustard
  publication-title: Fundam. Appl. Toxicol.
  doi: 10.1016/0272-0590(91)90203-G
– volume: 117
  start-page: 104
  year: 1992
  ident: 10.1016/j.toxlet.2020.01.024_bib0840
  article-title: Sulfur mustard-induced microvesication in hairless guinea pigs: effect of short-term niacinamide administration
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/0041-008X(92)90223-F
– volume: 1203
  start-page: 92
  year: 2010
  ident: 10.1016/j.toxlet.2020.01.024_bib0345
  article-title: Oxidants and antioxidants in sulfur mustard-induced injury
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2010.05605.x
– volume: 45
  start-page: 187
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0745
  article-title: Sulfur mustard causes oxidants/antioxidants imbalance through the overexpression of free radical producing-related genes in human mustard lungs
  publication-title: Environ. Toxicol. Pharmacol.
  doi: 10.1016/j.etap.2016.06.001
– volume: 31
  start-page: 3
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0070
  article-title: A review on proteomics analysis to reveal biological pathways and predictive proteins in sulfur mustard exposed patients: roles of inflammation and oxidative stress
  publication-title: Inhal. Toxicol.
  doi: 10.1080/08958378.2018.1558316
– volume: 115
  start-page: E1876
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0235
  article-title: NAD(+) supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1718819115
– volume: 130
  start-page: 1095
  year: 2007
  ident: 10.1016/j.toxlet.2020.01.024_bib0820
  article-title: Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
  publication-title: Cell
  doi: 10.1016/j.cell.2007.07.035
– volume: 31
  start-page: 1607
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0180
  article-title: NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells
  publication-title: Anticancer Res.
– volume: 91
  start-page: 39
  year: 1994
  ident: 10.1016/j.toxlet.2020.01.024_bib0385
  article-title: Detection of sulfur mustard-induced DNA modifications
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/0009-2797(94)90005-1
– volume: 119
  start-page: 197
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0535
  article-title: A review on symptoms, treatments protocols, and proteomic profile in sulfur mustard-exposed victims
  publication-title: J. Cell. Biochem.
  doi: 10.1002/jcb.26247
– volume: 108
  start-page: 28
  year: 2011
  ident: 10.1016/j.toxlet.2020.01.024_bib0310
  article-title: Involvement of calmodulin kinase II in the action of sulphur mustard on the contraction of vascular smooth muscle
  publication-title: Basic Clin. Pharmacol. Toxicol.
  doi: 10.1111/j.1742-7843.2010.00623.x
– volume: 98
  start-page: 159
  year: 1989
  ident: 10.1016/j.toxlet.2020.01.024_bib0490
  article-title: NAD+ levels and glucose uptake of cultured human epidermal cells exposed to sulfur mustard
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/0041-008X(89)90143-9
– volume: 74
  start-page: 3347
  year: 2017
  ident: 10.1016/j.toxlet.2020.01.024_bib0240
  article-title: Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells
  publication-title: Cell. Mol. Life Sci.: CMLS
  doi: 10.1007/s00018-017-2527-8
– volume: 9
  start-page: 9772
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0110
  article-title: Safety and metabolism of long-term administration of NIAGEN (Nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-46120-z
– volume: 8
  start-page: 129
  year: 1992
  ident: 10.1016/j.toxlet.2020.01.024_bib0115
  article-title: Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-L-cysteine or dexamethasone
  publication-title: Cell Biol. Toxicol.
  doi: 10.1007/BF00260563
– volume: 33
  start-page: 32
  year: 2014
  ident: 10.1016/j.toxlet.2020.01.024_bib0550
  article-title: Selected ebselen analogs reduce mechlorethamine toxicity in vitro
  publication-title: Cutan. Ocul. Toxicol.
  doi: 10.3109/15569527.2013.794818
– volume: 280
  start-page: 21313
  year: 2005
  ident: 10.1016/j.toxlet.2020.01.024_bib0365
  article-title: Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M413296200
– volume: 96
  start-page: 249
  year: 1995
  ident: 10.1016/j.toxlet.2020.01.024_bib0855
  article-title: Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin
  publication-title: Chem. Biol. Interact.
  doi: 10.1016/0009-2797(94)03596-Z
– start-page: 75
  year: 2006
  ident: 10.1016/j.toxlet.2020.01.024_bib0220
– volume: 42
  start-page: 217
  year: 2016
  ident: 10.1016/j.toxlet.2020.01.024_bib0740
  article-title: Oxidative stress and altered expression of peroxiredoxin genes family (PRDXS) and sulfiredoxin-1 (SRXN1) in human lung tissue following exposure to sulfur mustard
  publication-title: Exp. Lung Res.
  doi: 10.1080/01902148.2016.1194501
– volume: 80
  start-page: 2199
  year: 2007
  ident: 10.1016/j.toxlet.2020.01.024_bib0700
  article-title: Apoptosis in sulfur mustard treated A549 cell cultures
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2006.11.052
– volume: 328
  start-page: 732
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0185
  article-title: A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection
  publication-title: J. Pharmacol. Exp. Ther.
  doi: 10.1124/jpet.108.145037
– volume: 231
  start-page: 30
  year: 2007
  ident: 10.1016/j.toxlet.2020.01.024_bib0250
  article-title: Dose- and time-dependent effects of sulfur mustard on antioxidant system in liver and brain of rat
  publication-title: Toxicology
  doi: 10.1016/j.tox.2006.11.048
– volume: 188
  start-page: 263
  year: 2009
  ident: 10.1016/j.toxlet.2020.01.024_bib0705
  article-title: Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2009.04.012
– volume: 202
  start-page: 180
  year: 2005
  ident: 10.1016/j.toxlet.2020.01.024_bib0770
  article-title: Differential toxicity of sulfur mustard administered through percutaneous, subcutaneous, and oral routes
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2004.06.020
– volume: 5
  start-page: S134
  year: 1985
  ident: 10.1016/j.toxlet.2020.01.024_bib0540
  article-title: Molecular basis for mustard-induced vesication
  publication-title: Fundam. Appl. Toxicol.
  doi: 10.1016/0272-0590(85)90123-X
– volume: 293
  start-page: 21
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0875
  article-title: Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: are DNA adducts suitable biomarkers of exposure?
  publication-title: Toxicol. Lett.
  doi: 10.1016/j.toxlet.2017.12.014
– volume: 84
  start-page: 185
  year: 1993
  ident: 10.1016/j.toxlet.2020.01.024_bib0845
  article-title: Pathogenesis of 2,2’-dichlorodiethyl sulfide in hairless guinea pigs
  publication-title: Toxicology
  doi: 10.1016/0300-483X(93)90116-A
– volume: 40
  start-page: 290
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0350
  article-title: Sulfur mustard triggers oxidative stress through glutathione depletion and altered expression of glutathione-related enzymes in human airways
  publication-title: Immunopharmacol. Immunotoxicol.
  doi: 10.1080/08923973.2018.1460754
– volume: 17
  start-page: 89
  year: 2018
  ident: 10.1016/j.toxlet.2020.01.024_bib0785
  article-title: Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1alpha/mitochondrial biosynthesis pathway
  publication-title: Redox Biol.
  doi: 10.1016/j.redox.2018.04.006
– volume: 11
  year: 2019
  ident: 10.1016/j.toxlet.2020.01.024_bib0585
  article-title: Metabolic regulation of redox balance in cancer
  publication-title: Cancers
  doi: 10.3390/cancers11070955
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Snippet •Sulfur mustard (SM) and its derivatives are potent toxicants.•The molecular mechanisms behind SM-induced toxicity are not fully understood.•The paper...
Sulfur mustard (SM) is a toxicant and chemical warfare agent with strong vesicant properties. The mechanisms behind SM-induced toxicity are not fully...
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SubjectTerms Animals
Chemical Warfare Agents - toxicity
Cytotoxicity
Dietary Supplements
Humans
Mustard Gas - toxicity
NAD
NAD - administration & dosage
NAD - physiology
Niacinamide - administration & dosage
Nicotinamide adenine dinucleotide
Oxidative Stress - drug effects
PARP
Poly(ADP-ribose) Polymerases - metabolism
Reactive Nitrogen Species - metabolism
Sirtuins
Sirtuins - antagonists & inhibitors
Sulfur mustard
Title NAD+ in sulfur mustard toxicity
URI https://dx.doi.org/10.1016/j.toxlet.2020.01.024
https://www.ncbi.nlm.nih.gov/pubmed/32017979
https://www.proquest.com/docview/2351502997
Volume 324
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