Toxicological effects of nanoparticles in plants: Mechanisms involved at morphological, physiological, biochemical and molecular levels

• Published in: Plant physiology and biochemistry Vol. 210; p. 108604
• Main Authors: Gowtham, H.G., Shilpa, N., Singh, S. Brijesh, Aiyaz, Mohammed, Abhilash, M.R., Nataraj, K., Amruthesh, K.N., Ansari, Mohammad Azam, Alomary, Mohammad N., Murali, M.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.05.2024
• Subjects: Antioxidant; Genotoxicity; Nanoparticles; Nanoparticles - chemistry; Nanoparticles - toxicity; Nanopollution; Nanoremediation; Oxidative Stress - drug effects; Photosynthesis; Phytotoxicity; Plants - drug effects; Plants - metabolism; Reactive Oxygen Species - metabolism; Nanoparticles; Phytotoxicity; Genotoxicity; Nanopollution; Nanoremediation; Antioxidant; Photosynthesis
• ISSN: 0981-9428; 1873-2690
• DOI: 10.1016/j.plaphy.2024.108604

The rapid advancement of nanotechnology has led to unprecedented innovations across diverse industries, including pharmaceuticals, agriculture, cosmetics, electronics, textiles, and food, owing to the unique properties of nanoparticles. The extensive production and unregulated release of synthetic nanoparticles may contribute to nanopollution within the ecosystem. In the agricultural sector, nanotechnology is increasingly utilized to improve plant productivity, enhance resistance to stressors, and reduce the usage of chemicals. However, the uncontrolled discharge of nanoparticles into the natural environment raises concerns regarding possible plant toxicological impacts. The review focuses on the translocation of these particles within the plants, emphasizing their phytotoxicological effects at morphological, physiological, biochemical, and molecular levels. Eventhough the beneficial aspects of these nanoparticles are evident, excessive usage of nanoparticles at higher concentrations may lead to potential adverse effects. The phytotoxicity resulting from excessive amounts of nanoparticles affects seed germination and biomass production, disrupts the photosynthesis system, induces oxidative stress, impacts cell membrane integrity, alters gene expression, causes DNA damage, and leads to epigenetic variations in plants. Nanoparticles are found to directly associate with the cell membrane and cell organelles, leading to the dissolution and release of toxic ions, generation of reactive oxygen species (ROS) and subsequent oxidative stress. The present study signifies and accumulates knowledge regarding the application of nanoparticles in agriculture and illustrates a clear picture of their possible impacts on plants and soil microbes, thereby paving the way for future developments in nano-agrotechnology. The review concludes by addressing current challenges and proposing future directions to comprehend and mitigate the possible biological risks associated with nanoparticles in agriculture. •Nanoparticles exert beneficial effects at lower doses and adverse effects at higher doses.•Nanoparticles are primarily absorbed by roots, translocated and eventually accumulated in other aerial parts of plants.•Elevated levels of nanoparticles inhibit seed germination, plant growth and biomass.•Nanoparticles disrupt photosynthesis, induce oxidative stress, and impact cell membrane integrity.•Nanoparticles alter gene expression, cause DNA damage, and lead to plant epigenetic variations.