Unusual presentation of cystic fibrosis as diffuse dermatitis

• Published in: Indian journal of dermatology, venereology, and leprology Vol. 84; no. 4; pp. 461 - 463
• Main Authors: Bonfim, Bianca, Mota, Laís, Almeida, Carolina, de Brito Aguiar, Ana, Ferreira de Lima, Renata, de Mattos, Ângela, Souza, Edna
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.07.2018; Scientific Scholar
• Subjects: Anemia; Antibiotics; Child; Consent; Cystic fibrosis; Cystic Fibrosis - complications; Cystic Fibrosis - diagnosis; Cystic Fibrosis - therapy; Dermatitis; Dermatitis - diagnosis; Dermatitis - etiology; Dermatitis - therapy; Diagnosis, Differential; Eczema; Edema; Enzymes; Fatty acids; Follow-Up Studies; Guardians; Humans; Infant; Laboratories; Male; Malnutrition; Pediatrics; Skin; Brazil
• ISSN: 0378-6323; 0973-3922; 1998-3611
• DOI: 10.4103/ijdvl.IJDVL_616_17

Differential diagnosis of this kind of rash without associated systemic manifestations includes atopic dermatitis, psoriasis, seborrheic dermatitis, Langerhans cell histiocytosis, immunodeficiency syndromes and acrodermatitis enteropathica. The etiopathogenesis of the skin changes in cystic fibrosis still remain elusive, but it is apparently related to concomitant deficiencies of protein, zinc, essential fatty acids and possibly copper. [1] Early diagnosis and proper cystic fibrosis treatment are crucial for this clinical presentation since it is associated with poor prognosis and the lesions may evolve with secondary infection and septicemia, a life-threatening condition whose sequelae can be severe and progress to death.