Analysis of the interaction of 16S rRNA and cytoplasmic membrane with the C‐terminal part of the Streptococcus pneumoniae Era GTPase

• Published in: European journal of biochemistry Vol. 268; no. 21; pp. 5570 - 5577
• Main Authors: Hang, Julie Qi, Meier, Timothy I., Zhao, Genshi
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.11.2001
• Subjects: 16S rRNA; Amino Acid Sequence; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Base Sequence; Binding Sites; Cell Division - genetics; Conserved Sequence; Cytoplasm - metabolism; Era GTPase; Escherichia coli - genetics; Escherichia coli Proteins; Genetic Complementation Test; GTP Phosphohydrolases - genetics; GTP Phosphohydrolases - metabolism; GTP-Binding Proteins - genetics; GTP-Binding Proteins - metabolism; Intracellular Membranes - metabolism; KH domain; Membrane Proteins - genetics; Membrane Proteins - metabolism; membrane‐binding; Molecular Sequence Data; Mutation; RNA, Bacterial - metabolism; RNA, Ribosomal, 16S - metabolism; RNA-Binding Proteins; RNA‐binding; Streptococcus pneumoniae - metabolism

Era, an essential GTPase, plays a regulatory role in several cellular processes. The Era protein of Streptococcus pneumoniae has recently been shown to bind to 16S rRNA and the cytoplasmic membrane. However, exact locations of Era responsible for RNA‐ and membrane‐binding were unknown. To identify t...