Drug interactions in the intensive care unit

Adverse drug reactions are a major source of complications in the intensive care unit. Drug interactions contribute significantly to the incidence of adverse drug reactions. The intensive care unit clinician must remain aware of the major mechanisms for drug interactions, which are reviewed in this...

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Bibliographic Details
Published inClinics in chest medicine Vol. 20; no. 2; p. 385
Main Authors Romac, D R, Albertson, T E
Format Journal Article
LanguageEnglish
Published United States 01.06.1999
Subjects
Age Distribution
Aged
Critical Illness - therapy
Cytochrome P-450 Enzyme System - metabolism
Dose-Response Relationship, Drug
Drug Interactions
Drug Therapy, Combination
Female
Humans
Intensive Care Units
Male
Pharmacokinetics
Risk Assessment
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Summary:Adverse drug reactions are a major source of complications in the intensive care unit. Drug interactions contribute significantly to the incidence of adverse drug reactions. The intensive care unit clinician must remain aware of the major mechanisms for drug interactions, which are reviewed in this article.
ISSN:0272-5231
1557-8216
DOI:10.1016/S0272-5231(05)70148-9