Contactless Monitoring of Microcirculation Reaction on Local Temperature Changes

• Published in: Applied sciences Vol. 9; no. 22; p. 4947
• Main Authors: Volynsky, Maxim A., Margaryants, Nikita B., Mamontov, Oleg V., Kamshilin, Alexei A.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2019
• Subjects: Blood flow; blood microcirculation; Blood vessels; Capillary flow; Diabetes mellitus; Digital cameras; Dyslipidemia; EKG; Electrocardiography; Exposure; Forehead; Health risks; Heart rate; Heat; Hypertension; imaging photoplethysmography; Laboratories; Medical equipment; Medical imaging; Medical research; Patients; Polarized light; Reactivity; Skin; Skin temperature; Temperature effects; Thermoregulation; Russia
• ISSN: 2076-3417; 2076-3417
• DOI: 10.3390/app9224947

Assessment of skin blood flow is an important clinical task which is required to study mechanisms of microcirculation regulation including thermoregulation. Contactless assessment of vasomotor reactivity in response to thermal exposure is currently not available. The aim of this study is to show the applicability of the imaging photoplethysmography (IPPG) method to measure quantitatively the vasomotor response to local thermal exposure. Seventeen healthy subjects aged 23 ± 7 years participated in the study. A warm transparent compress applied to subject’s forehead served as a thermal impact. A custom-made IPPG system operating at green polarized light was used to monitor the subject’s face continuously and simultaneously with skin temperature and electrocardiogram (ECG) recordings. We found that the thermal impact leads to an increase in the amplitude of blood pulsations (BPA) simultaneously with the skin temperature increase. However, a multiple increase in BPA remained after the compress was removed, whereas the skin temperature returned to the baseline. Moreover, the BPA increase and duration of the vasomotor response was associated with the degree of external heating. Therefore, the IPPG method allows us to quantify the parameters of capillary blood flow during local thermal exposure to the skin. This proposed technique of assessing the thermal reactivity of microcirculation can be applied for both clinical use and for biomedical research.