Antenatal corticosteroids for fetal maturation in women at risk for preterm delivery

The available data unambiguously support the beneficial, short-term fetal effects of antenatal corticosteroids in women at risk for preterm delivery. There are still several incompletely addressed questions, including the use of corticosteroids in women with preterm premature rupture of membranes, t...

Full description

Saved in:
Bibliographic Details
Published inClinics in perinatology Vol. 30; no. 4; p. 825
Main Authors Vidaeff, Alex C, Doyle, Nora M, Gilstrap, 3rd, Larry C
Format Journal Article
LanguageEnglish
Published United States 01.12.2003
Subjects
Adrenal Cortex Hormones - administration & dosage
Adrenal Cortex Hormones - pharmacology
Betamethasone - administration & dosage
Betamethasone - pharmacology
Consensus Development Conferences, NIH as Topic
Dexamethasone - administration & dosage
Dexamethasone - pharmacology
Female
Fetal Membranes, Premature Rupture - complications
Fetal Organ Maturity - drug effects
Gestational Age
Humans
Obstetric Labor, Premature - etiology
Obstetric Labor, Premature - prevention & control
Pregnancy
Pregnancy Outcome
United States
United States
Online AccessGet more information

Cover

More Information
Summary:The available data unambiguously support the beneficial, short-term fetal effects of antenatal corticosteroids in women at risk for preterm delivery. There are still several incompletely addressed questions, including the use of corticosteroids in women with preterm premature rupture of membranes, the optimal corticosteroid preparation to be used, and the impact of repeated dosing. These issues are discussed in this review from the perspective of recent scientific evidence on the mechanisms responsible for positive short-term effects on survival and possible harmful long-term effects.
ISSN:0095-5108
DOI:10.1016/S0095-5108(03)00102-7