Repeat testing enhances long-term verbal memory in children with epilepsy

• Published in: Child neuropsychology Vol. 30; no. 3; pp. 425 - 443
• Main Authors: Joplin, Samantha, Gascoigne, Michael, Barton, Belinda, Webster, Richard, Gill, Deepak, Lawson, John, Mandalis, Anna, Sabaz, Mark, McLean, Samantha, Gonzalez, Linda, Smith, Mary-Lou, Lah, Suncica
• Format: Journal Article
• Language: English
• Published: England Routledge 02.04.2024
• Subjects: Accelerated Long-term Forgetting (ALF); Child; Epilepsy - complications; Epilepsy, Temporal Lobe; executive functioning in children; Genetic Generalised Epilepsy (GGE); Humans; Memory; Memory Disorders; Memory, Long-Term; Mental Recall; Neuropsychological Tests; repeat testing and memory retention; Temporal Lobe Epilepsy (TLE); Genetic Generalised Epilepsy (GGE); repeat testing and memory retention; executive functioning in children; Accelerated Long-term Forgetting (ALF); Temporal Lobe Epilepsy (TLE)
• ISSN: 0929-7049; 1744-4136
• DOI: 10.1080/09297049.2023.2205633

To (i) determine whether accelerated long-term forgetting (ALF) can be found using standardized verbal memory test materials in children with genetic generalized epilepsy (GGE) and temporal lobe epilepsy (TLE), and (ii) to establish whether ALF is impacted by executive skills and repeat testing over long delays. One hundred and twenty-three children aged 8 to 16, (28 with GGE, 23 with TLE, and 72 typically developing; TD) completed a battery of standardized tests assessing executive functioning and memory for two stories. Stories were recalled immediately and after a 30-min delay. To examine whether repeat testing impacts long-term forgetting, one story was tested via free recall at 1-day and 2-weeks, and the other at 2-weeks only. Recognition was then tested for both stories at 2-weeks. Children with epilepsy recalled fewer story details, both immediately and after 30-min relative to TD children. Compared to TD children, the GGE group, but not the TLE group, showed ALF, having significantly poorer recall of the story tested only at the longest delay. Poor executive skills were significantly correlated with ALF for children with epilepsy. Standard story memory materials can detect ALF in children with epilepsy when administered over long delays. Our findings suggest that (i) ALF is related to poor executive skills in children with epilepsy, and (ii) repeated testing may ameliorate ALF in some children.