Health-Related Quality of Life in Patients with Sleep-Related Breathing Disorders: Relationship with Nocturnal Parameters, Daytime Symptoms and Comorbid Diseases

• Published in: Respiration Vol. 75; no. 4; pp. 393 - 401
• Main Authors: Gülbay, Banu Eriş, Acıcan, Turan, Önen, Zeynep Pınar, Yıldız, Öznur Akkoca, Baççıoğlu, Ayşe, Arslan, Fatma, Köse, Kenan
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.2008; S. Karger AG
• Subjects: Adult; Aged; Biological and medical sciences; Clinical Investigations; Comorbidity; Correlation analysis; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes; Female; Humans; Male; Medical sciences; Middle Aged; Nervous system (semeiology, syndromes); Neurology; Pneumology; Polysomnography; Quality of Life; Respiratory system; Sleep - physiology; Sleep apnea; Sleep Apnea, Obstructive - physiopathology; Sleep disorders; Snoring - physiopathology; Sleep-related breathing disorders; Epworth Sleepiness Scale; Medical Outcome Survey - Short Form 36; Polysomnography; Charlson comorbidity index; Quality of life; Human; Nervous system diseases; Prognosis; Disease; Health; Sleep disorder; Sleep-related breathing disorders . Quality of life . Polysomnography . Medical Outcome Survey; Medicine; Electrodiagnosis; Symptomatology; Concomitant disease; Survey; Surveillance; Evolution; Short Form 36 . Epworth Sleepiness Scale . Charlson comorbidity index; Neurological disorder; Pneumology
• ISSN: 0025-7931; 1423-0356
• DOI: 10.1159/000104865

Background: Sleep-related breathing disorders (SRBD) are frequently encountered health problems in the general population. Habitual snoring and obstructive sleep apnea/hypopnea syndrome (OSAHS) constitute most SRBD diagnoses. Although the decrease in quality of life is a well-known entity in SRBD patients, there is not enough data regarding the underlying pathophysiological mechanisms to explain this deterioration. Objectives: The aim of this study was to investigate which parameters were affecting the quality of life in patients with SRBD. Methods: Medical Outcome Survey – Short Form 36 (SF-36) and Epworth Sleepiness Scale were used in 135 patients with SRBD (69 patients with OSAHS and 66 patients with habitual snoring), and Charlson comorbidity index was calculated. Acquired data were compared with leading symptoms and polysomnographic findings in these patients. Results: All SF-36 scores were significantly decreased in SRBD patients. However, there were no significant differences in the SF-36 scores of these patients. Also, no significant correlation was found between the severity of OSAHS and the SF-36 scores. Similarly, none of the polysomnographic parameters was found significantly correlated with SF-36 scores. In contrast, all SF-36 scores were influenced by body mass index, Epworth Sleepiness Scale score, mean nocturnal saturation and the presence of coexisting diseases. Conclusions: According to the results of multiple variance analysis, we concluded that the quality of life depends on a number of collaborative factors such as obesity, mean nocturnal saturation, symptoms related to SRBD and the presence of comorbid diseases, rather than only on one independent parameter in the patients with SRBD.