Pathology of the Placenta in Singletons after Assisted Reproductive Technology Compared to Singletons after Spontaneous Conception: A Systematic Review

Background: We reviewed the literature comparing the pathological characteristics of singleton births conceived after assisted reproductive technology (ART) with those after spontaneous conception. Methods: We reviewed PubMed, EMBASE, Ovid MEDLINE, Google Scopus, Scholar, Cochrane Central Register o...

Full description

Saved in:
Bibliographic Details
Published inFetal and pediatric pathology Vol. 42; no. 3; pp. 438 - 449
Main Authors Belak, Urška, Pinter, Bojana, Ban Frangež, Helena, Velikonja, Mojca, Korošec, Sara
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 04.05.2023
Subjects
assisted reproductive technology
embryo transfer
Female
Humans
in vitro fertilization
pathology
Placenta
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Reproductive Techniques, Assisted - adverse effects
in vitro fertilization
assisted reproductive technology
Placenta
pathology
embryo transfer
Online AccessGet full text

Cover

More Information
Summary:Background: We reviewed the literature comparing the pathological characteristics of singleton births conceived after assisted reproductive technology (ART) with those after spontaneous conception. Methods: We reviewed PubMed, EMBASE, Ovid MEDLINE, Google Scopus, Scholar, Cochrane Central Register of Controlled Trials and the Web of Science for the previous 10 years, up to November 2022. Results: Four eligible studies included 3445 placentas, 806 after ART (IVF/ICSI). Placentas after ART differed in frequency of retroplacental and marginal hematomas (p = 0.04), increased thickness (p = 0.02), higher overall occurrences of vascular and anatomical pathology (p < 0.001) and more frequent marginal (p = 0.001) and membranous (p = 0.02) umbilical cord insertion than placentas from non-ART pregnancies. Conclusion: Further research is needed to determine the extent to which these placental changes in ART pregnancies alter its function and pregnancy outcome.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
ISSN:1551-3815
1551-3823
DOI:10.1080/15513815.2022.2157228