New-types of apparatus for producing microcapsules and microgranules
Two types of simple compact apparatuses for microencapsulation and microgranulation have been developed. The vibration-type apparatus is a better fit for producing gel-like microgranules of 1.5–3.0 mm in diameter to be used in production of food (fodder) products and additives and microgranulated ce...
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Published in | International journal of pharmaceutics Vol. 242; no. 1; pp. 101 - 106 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
21.08.2002
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Subjects | |
Online Access | Get full text |
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Summary: | Two types of simple compact apparatuses for microencapsulation and microgranulation have been developed. The vibration-type apparatus is a better fit for producing gel-like microgranules of 1.5–3.0 mm in diameter to be used in production of food (fodder) products and additives and microgranulated cell culture. The spray apparatus is fit for operation in two modes: drop-forming (particles of 100–500 μm in diameter) and spray modes (particles of 10–50 μm in diameter). The apparatus is most efficient when used in the mode of forming the particles directly in the medium of liquid nitrogen with successive lyophilic drying (without preliminary defrosting). It is used for microgranulating the live virus materials with their virulence being preserved. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0378-5173 1873-3476 |
DOI: | 10.1016/S0378-5173(02)00156-4 |