Bispidine-Based Macrocycles: Achievements and Perspectives

• Published in: Organics (Basel) Vol. 4; no. 3; pp. 417 - 437
• Main Authors: Medved’ko, Aleksei V., Gaisen, Savelii V., Kalinin, Mikhail A., Vatsadze, Sergey Z.
• Format: Journal Article
• Language: English
• Published: Leuven MDPI AG 01.09.2023
• Subjects: 3,7-diazabicyclo[3.3.1]nonane; bispidine; Copper; crown ethers; Hydrogen bonds; macroheterocycles; Mannich reaction; Nitrogen; supramolecular chemistry

This review presents all currently known macroheterocyclic compounds that include a bispidine (3,7-diazabicyclo[3.3.1]nonane) fragment in their structure. A classification of bispidine-containing macroheterocycles, which is based on the ring size and the nature of bispidinic nitrogen atoms, is sugge...