Phthalates: toxicology and food safety - a review

Phthalates are organic substances used mainly as plasticisers in the manufacture of plastics. They are ubiquitous in the environment. Although tests in rodents have demonstrated numerous negative effects of phthalates, it is still unclear whether the exposure to phthalates may also damage human heal...

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Bibliographic Details
Published inCzech Journal of Food Sciences Vol. 23; no. 6; pp. 217 - 223
Main Authors Mikula, Přemysl, Svobodová, Zdeňka, Smutná, Miriam
Format Journal Article
LanguageEnglish
Published Prague Czech Academy of Agricultural Sciences (CAAS) 01.01.2005
Czech Academy of Agricultural Sciences
Subjects
di(2-ethylhexyl)phthalate
dibutyl phthalate
Food safety
peroxisome proliferators
Phthalates
reproductive toxicity
Toxicity
Toxicology
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Summary:Phthalates are organic substances used mainly as plasticisers in the manufacture of plastics. They are ubiquitous in the environment. Although tests in rodents have demonstrated numerous negative effects of phthalates, it is still unclear whether the exposure to phthalates may also damage human health. This paper describes phthalate toxicity and toxicokinetics, explains the mechanisms of phthalate action, and outlines the issues relating to the presence of phthalates in foods.
ISSN:1212-1800
1805-9317
DOI:10.17221/3394-CJFS