A Risk-Benefit Review of Currently Used Dermal Substitutes for Burn Wounds

While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive option. There are many advantages of utilizing a dermal substitute, notably reducing the need for donor tissue and subsequent iatrogenic creat...

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Published inJournal of burn care & research Vol. 44; no. Suppl_1; p. S26
Main Authors Hill, David M, Hickerson, William L, Carter, Jeffrey E
Format Journal Article
LanguageEnglish
Published England 02.01.2023
Subjects
Burns - surgery
Humans
Risk Assessment
Skin Transplantation - methods
Skin, Artificial
Transplantation, Autologous
Wound Healing
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Abstract While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive option. There are many advantages of utilizing a dermal substitute, notably reducing the need for donor tissue and subsequent iatrogenic creation of a secondary wound. However, there are disadvantages with each that most be weighed and factored into the decision. And most come at a high initial financial cost. There is little comparative literature of the various available and emerging products. This analysis was performed to objectively present risks and benefits of each option.
AbstractList While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive option. There are many advantages of utilizing a dermal substitute, notably reducing the need for donor tissue and subsequent iatrogenic creation of a secondary wound. However, there are disadvantages with each that most be weighed and factored into the decision. And most come at a high initial financial cost. There is little comparative literature of the various available and emerging products. This analysis was performed to objectively present risks and benefits of each option.
Author Hill, David M
Carter, Jeffrey E
Hickerson, William L
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  organization: Louisiana State University Health Sciences Center, 2000 Canal Street, New Orleans, Louisiana 70112, USA
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Copyright The Author(s) 2022. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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Snippet While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive...
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StartPage S26
SubjectTerms Burns - surgery
Humans
Risk Assessment
Skin Transplantation - methods
Skin, Artificial
Transplantation, Autologous
Wound Healing
Title A Risk-Benefit Review of Currently Used Dermal Substitutes for Burn Wounds
URI https://www.ncbi.nlm.nih.gov/pubmed/36567472
Volume 44
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