A Risk-Benefit Review of Currently Used Dermal Substitutes for Burn Wounds

While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive option. There are many advantages of utilizing a dermal substitute, notably reducing the need for donor tissue and subsequent iatrogenic creat...

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Bibliographic Details
Published inJournal of burn care & research Vol. 44; no. Suppl_1; p. S26
Main Authors Hill, David M, Hickerson, William L, Carter, Jeffrey E
Format Journal Article
LanguageEnglish
Published England 02.01.2023
Subjects
Burns - surgery
Humans
Risk Assessment
Skin Transplantation - methods
Skin, Artificial
Transplantation, Autologous
Wound Healing
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Summary:While split-thickness autologous skin grafts remain the most common method of definitive burn wound closure, dermal substitutes have emerged as an attractive option. There are many advantages of utilizing a dermal substitute, notably reducing the need for donor tissue and subsequent iatrogenic creation of a secondary wound. However, there are disadvantages with each that most be weighed and factored into the decision. And most come at a high initial financial cost. There is little comparative literature of the various available and emerging products. This analysis was performed to objectively present risks and benefits of each option.
ISSN:1559-0488
DOI:10.1093/jbcr/irac131