Vulnerable plaque imaging and acute coronary syndrome

Abstract The term vulnerable plaque has been established to describe an atherosclerotic lesion with a high probability of causing a future coronary event [1,2] . The identification and stabilization of the lesion before its rupture may reduce the morbidity and mortality caused by coronary artery dis...

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Bibliographic Details
Published inCor et vasa (English ed.) Vol. 56; no. 4; pp. e362 - e368
Main Authors Horváth, Martin, Hájek, Petr, Štěchovský, Cyril, Veselka, Josef
Format Journal Article
LanguageEnglish
Published Elsevier Urban & Partner Sp. z o.o 01.08.2014
Subjects
Cardiovascular
Intravascular ultrasound
Lipid-core plaque
Near-infrared spectroscopy
Optical coherence tomography
Thin-cap fibroatheroma
Vulnerable plaque
Lipid-core plaque
Vulnerable plaque
Optical coherence tomography
Intravascular ultrasound
Thin-cap fibroatheroma
Near-infrared spectroscopy
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Summary:Abstract The term vulnerable plaque has been established to describe an atherosclerotic lesion with a high probability of causing a future coronary event [1,2] . The identification and stabilization of the lesion before its rupture may reduce the morbidity and mortality caused by coronary artery disease. Modern imaging modalities such as computer tomography coronary angiography, intravascular ultrasound, optical coherence tomography and near-infrared spectroscopy have a potential in finding these vulnerable plaques. This raises opportunities in the primary and secondary prevention of coronary artery disease. This review summarizes the current knowledge with an emphasis put on the research advances in the field of near-infrared spectroscopy a modality that has been intentionally developed for the detection of lipid-core plaques.
ISSN:0010-8650
1803-7712
DOI:10.1016/j.crvasa.2014.05.002