Prevalence of Immunoglobulin G (IgG) Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Evaluation of a Rapid MEDsan IgG Test in Children Seeking Medical Care

Abstract In 208 children seeking medical care, the seropositivity rate of anti–SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR–confirmed pediatric cases. Compared with the gold-standard combined ELISA + immu...

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Published inClinical infectious diseases Vol. 72; no. 7; pp. e192 - e195
Main Authors Posfay-Barbe, Klara M, Andrey, Diego O, Virzi, Julien, Cohen, Patrick, Pigny, Fiona, Goncalves, Ana R, Pinosch, Selina, Lacroix, Laurence, Stringhini, Silvia, Kaiser, Laurent, Vuilleumier, Nicolas, L’Huillier, Arnaud G
Format Journal Article
LanguageEnglish
Published US Oxford University Press 08.04.2021
Subjects
Adult
Antibodies, Viral
Child
COVID-19
Humans
Immunoglobulin G
Immunoglobulin M
Prevalence
SARS-CoV-2
COVID-19
seroprevalence
rapid diagnostic test
antibody
pediatrics
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Summary:Abstract In 208 children seeking medical care, the seropositivity rate of anti–SARS-CoV-2 IgG antibodies was 8.7%, suggesting an infection rate similar to that observed in adults but >100-fold the incidence of RT-PCR–confirmed pediatric cases. Compared with the gold-standard combined ELISA + immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa1702